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肿瘤还是炎症?一例原发性肺绒毛膜癌病例报告

The tumor or inflammation? a case report on primary pulmonary choriocarcinoma.

作者信息

Wang Na, Zhang Nan, Zhang Xinyue, Wang Yuanyuan, Fu Yajie, Guo Lingfei, Liang Changhu, Yu Mengru

机构信息

Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Department of Medical Imaging, Binzhou Medical University, Yantai, Shandong, China.

出版信息

Front Oncol. 2023 Jul 13;13:1108798. doi: 10.3389/fonc.2023.1108798. eCollection 2023.

DOI:10.3389/fonc.2023.1108798
PMID:37519783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10372341/
Abstract

Choriocarcinoma is a rare malignant germ cell neoplasm with high invasiveness, the majority of which are pregnancy-related, and the female genital tract is the most prevalent site of the disease. Although early-stage choriocarcinoma typically metastasizes to the lungs, primary pulmonary choriocarcinoma is extremely rare. Primary pulmonary choriocarcinoma is difficult to diagnose, and it progresses rapidly. Combined with the difficulty of treatment, the prognosis of patients is generally poor. In this article, we retrospectively analyzed a case of female primary pulmonary choriocarcinoma, combined with a review of literature, to understand and describe the diagnostic and treatment progress of PPC.

摘要

绒毛膜癌是一种罕见的具有高侵袭性的恶性生殖细胞肿瘤,其中大多数与妊娠相关,女性生殖道是该疾病最常见的部位。尽管早期绒毛膜癌通常转移至肺部,但原发性肺绒毛膜癌极为罕见。原发性肺绒毛膜癌难以诊断,且进展迅速。加上治疗困难,患者的预后通常较差。在本文中,我们回顾性分析了一例女性原发性肺绒毛膜癌病例,并结合文献复习,以了解和描述原发性肺绒毛膜癌的诊断和治疗进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/de4e875cdfd5/fonc-13-1108798-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/a6e38fd06413/fonc-13-1108798-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/a0ba921be224/fonc-13-1108798-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/de4e875cdfd5/fonc-13-1108798-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/a6e38fd06413/fonc-13-1108798-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/a0ba921be224/fonc-13-1108798-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7d8/10372341/de4e875cdfd5/fonc-13-1108798-g003.jpg

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引用本文的文献

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本文引用的文献

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Case report: Using DNA short tandem repeats to confirm nongestational origin of pulmonary choriocarcinoma.病例报告:利用DNA短串联重复序列确认肺绒毛膜癌的非妊娠起源。
Front Oncol. 2022 Oct 17;12:1001627. doi: 10.3389/fonc.2022.1001627. eCollection 2022.
2
Case Report: Treatment of primary pulmonary choriocarcinoma with lung lobectomy and adjuvant chemotherapy.病例报告:肺叶切除术联合辅助化疗治疗原发性肺绒毛膜癌
Gynecol Oncol Rep. 2022 Aug 27;43:101064. doi: 10.1016/j.gore.2022.101064. eCollection 2022 Oct.
3
Primary pulmonary choriocarcinoma in male: report a case with genetic testing and review of the literature.
男性原发性肺绒毛膜癌:一例基因检测报告并文献复习
Transl Cancer Res. 2022 Jun;11(6):1844-1849. doi: 10.21037/tcr-21-2627.
4
Effectiveness and Safety of Toripalimab Combination Therapies for Patients With Chemo-Resistant Choriocarcinoma.托法替布联合疗法治疗化疗耐药性绒毛膜癌患者的有效性和安全性。
Front Oncol. 2022 Apr 14;12:815917. doi: 10.3389/fonc.2022.815917. eCollection 2022.
5
Primary Pulmonary Choriocarcinoma Treated With Neoadjuvant Chemotherapy and Lobectomy: A Case Report.新辅助化疗联合肺叶切除术治疗原发性肺绒毛膜癌:一例报告
Cureus. 2022 Feb 5;14(2):e21931. doi: 10.7759/cureus.21931. eCollection 2022 Feb.
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Algorithmic Approach to the Diagnosis of Organizing Pneumonia: A Correlation of Clinical, Radiologic, and Pathologic Features.机化性肺炎诊断的算法方法:临床、放射学和病理学特征的相关性
Chest. 2022 Jul;162(1):156-178. doi: 10.1016/j.chest.2021.12.659. Epub 2022 Jan 14.
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Primary pulmonary choriocarcinoma with a genomic sequence.具有基因组序列的原发性肺绒毛膜癌。
Pathol Int. 2022 Feb;72(2):141-143. doi: 10.1111/pin.13193. Epub 2021 Dec 14.
8
Amenorrhea and elevated βhuman chorionic gonadotropin of unknown origin: An unexpected location of choriocarcinoma.不明原因的闭经和β人绒毛膜促性腺激素升高:绒毛膜癌的一个意外部位。
Gynecol Oncol Rep. 2021 Mar 13;36:100746. doi: 10.1016/j.gore.2021.100746. eCollection 2021 May.
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Clinical Experience of Male Primary Choriocarcinoma at the Samsung Medical Center.三星医疗中心男性原发性绒毛膜癌的临床经验。
Cancer Res Treat. 2021 Jul;53(3):874-880. doi: 10.4143/crt.2020.1066. Epub 2020 Dec 7.
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