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垂直牙槽嵴增高术中同种异体松质骨块的并发症:前瞻性临床病例研究及文献综述

Complications with allogeneic, cancellous bone blocks in vertical alveolar ridge augmentation: prospective clinical case study and review of the literature.

作者信息

Draenert Florian G, Kämmerer Peer W, Berthold Michael, Neff Andreas

机构信息

D Implant Institute, Tal 4, Munich, Germany; Extraordinary Professor for Oral & Maxillofacial Surgery, University of Marburg, Marburg, Germany.

Clinic for Oral & Maxillofacial Surgery, University of Rostock, Rostock, Germany.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Aug;122(2):e31-43. doi: 10.1016/j.oooo.2016.02.018. Epub 2016 Mar 17.

Abstract

OBJECTIVES

Vertical bone augmentation in dental implantology is an indication for cancellous allogeneic bone blocks (ABB). However, these materials may lead to adverse reactions, which are known well in orthopedics but rarely published. Therefore, in this study, we performed an evaluation of the use of ABB in vertical bone augmentation in clinical dental implantology.

STUDY DESIGN

The prospective clinical study included 20 cases with vertical augmentation using ABB and subsequent or simultaneous placement of implants in the lateral maxilla and mandible. Follow-up included panoramic radiography, tissue healing, and peri-implantitis. Because of the limited number of patients, the report was planned to be descriptive only. Loss of ABB or peri-implantitis of more than 30% of the intraosseous implant length was deemed to indicate failure.

RESULTS

The study was cancelled after six cases because of an unexpectedly high number of complications (5 of 6; 83%). The average surveillance time was 1460 days. Three types of unsatisfying outcome were observed: type I, early complete loss of the augmentation with soft tissue defects after 3 to 8 weeks (n = 2); type II, early soft tissue maceration (up to 8 weeks) without loss of coverage and complete early bone healing with later peri-implantitis and bone loss after prosthetic loading (6 months or later; n = 2); and type III, complication-free bone healing with subsequent peri-implantitis after prosthetic loading (6 months or later; n = 1).

CONCLUSIONS

Complications were observed in vertical augmentation with ABB and implant placement. After careful consideration, literature data were found to support these results and also suggest that tissue level implants may be advantageous in vertical bone augmentation with ABB.

摘要

目的

在牙种植学中,垂直骨增量是同种异体松质骨块(ABB)的一种适应证。然而,这些材料可能会导致不良反应,这在骨科领域广为人知,但鲜有报道。因此,在本研究中,我们对ABB在临床牙种植学垂直骨增量中的应用进行了评估。

研究设计

这项前瞻性临床研究纳入了20例使用ABB进行垂直骨增量并随后或同时在上颌骨和下颌骨外侧植入种植体的病例。随访包括全景X线摄影、组织愈合情况以及种植体周围炎。由于患者数量有限,本报告仅计划进行描述性分析。如果ABB丢失或种植体周围炎累及超过30%的骨内种植体长度,则视为失败。

结果

由于并发症数量意外之多(6例中有5例,83%),该研究在6例患者后取消。平均监测时间为1460天。观察到三种不尽人意的结果:I型,3至8周后增量骨早期完全丧失并伴有软组织缺损(n = 2);II型,早期软组织浸渍(长达8周)但覆盖未丧失,早期骨完全愈合,后期在修复体加载后(6个月或更晚)出现种植体周围炎和骨质流失(n = 2);III型,骨愈合无并发症,但在修复体加载后(6个月或更晚)出现种植体周围炎(n = 1)。

结论

在使用ABB进行垂直骨增量和种植体植入过程中观察到了并发症。经过仔细考虑,发现文献数据支持这些结果,并且还表明在使用ABB进行垂直骨增量时,组织水平种植体可能具有优势。

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