Duman Lale, Gezer Naciye S, Balcı Pınar, Altay Canan, Başara Işıl, Durak Merih G, Sevinç Ali I
Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Department of Pathology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Breast Care (Basel). 2016 Apr;11(2):123-7. doi: 10.1159/000444377. Epub 2016 Mar 23.
This study was performed to compare the mammographic, sonographic, and magnetic resonance imaging (MRI) characteristics of phyllodes tumors and fibroadenomas, which may resemble each other.
Preoperative mammograms, B-mode and Doppler sonograms, and dynamic breast MRIs of 72 patients with pathologically proven fibroadenomas and 70 patients with pathologically proven phyllodes tumor were evaluated in this retrospective study. Statistical significance was evaluated using chi-square and Fisher's exact tests. Correlations in lesion size among radiological methods were examined by Pearson's correlation analysis.
The features that differed on mammogram were size, shape, and margin of the mass. Sonograms showed significant differences in size, shape, margin, echo pattern, and vascularization of the mass. Pearson's correlation analysis showed strong agreement among radiological methods in terms of assessment of size. Tumor size ≥ 3 cm, irregular shape, microlobulated margins, complex internal echo pattern, and hypervascularity were significant findings of phyllodes tumors. Internal cystic areas on MRI were frequently associated with phyllodes tumors.
Mammographic, sonographic, and MRI findings of fibroadenomas and phyllodes tumors could help radiologists to ascertain imaging-histological concordance and guide clinicians in their decision making regarding adequate follow-up or the necessity of biopsy.
本研究旨在比较叶状肿瘤和纤维腺瘤在乳房X线摄影、超声和磁共振成像（MRI）上的特征，这两种肿瘤可能彼此相似。
本回顾性研究评估了72例经病理证实为纤维腺瘤的患者和70例经病理证实为叶状肿瘤的患者的术前乳房X线照片、B超和多普勒超声图像以及动态乳房MRI。使用卡方检验和费舍尔精确检验评估统计学意义。通过Pearson相关分析检查放射学方法之间病变大小的相关性。
乳房X线摄影上不同的特征是肿块的大小、形状和边缘。超声显示肿块在大小、形状、边缘、回声模式和血管形成方面存在显著差异。Pearson相关分析显示，在大小评估方面，放射学方法之间有很强的一致性。肿瘤大小≥3 cm、形状不规则、边缘呈微叶状、内部回声模式复杂和血管丰富是叶状肿瘤的显著表现。MRI上的内部囊性区域常与叶状肿瘤相关。
纤维腺瘤和叶状肿瘤的乳房X线摄影、超声和MRI表现可帮助放射科医生确定影像学与组织学的一致性，并指导临床医生在进行适当随访或活检必要性方面的决策。
