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急性肾损伤的生物标志物及其与短期和长期预后的关联。

Biomarkers of acute kidney injury and associations with short- and long-term outcomes.

作者信息

Schaub Jennifer A, Parikh Chirag R

机构信息

Program of Applied Translational Research, Yale University, New Haven, CT, USA.

出版信息

F1000Res. 2016 May 24;5. doi: 10.12688/f1000research.7998.1. eCollection 2016.

DOI:10.12688/f1000research.7998.1
PMID:27239295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4879936/
Abstract

Acute kidney injury is strongly associated with increased mortality and other adverse outcomes. Medical researchers have intensively investigated novel biomarkers to predict short- and long-term outcomes of acute kidney injury in many patient care settings, such as cardiac surgery, intensive care units, heart failure, and transplant. Future research should focus on leveraging this relationship to improve enrollment for clinical trials of acute kidney injury.

摘要

急性肾损伤与死亡率增加及其他不良后果密切相关。医学研究人员已在许多患者护理场景中,如心脏手术、重症监护病房、心力衰竭和移植等,深入研究新型生物标志物以预测急性肾损伤的短期和长期后果。未来的研究应侧重于利用这种关系来改善急性肾损伤临床试验的入组情况。

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Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial.甲泼尼龙琥珀酸钠在体外循环患者(全身炎症反应综合征)中的应用:一项随机、双盲、安慰剂对照试验。
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Associations between Deceased-Donor Urine Injury Biomarkers and Kidney Transplant Outcomes.
监管生物标志物资格认定过程中统计策略的观点。
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Elevated preoperative Galectin-3 is associated with acute kidney injury after cardiac surgery.术前半乳糖凝集素-3升高与心脏手术后急性肾损伤相关。
BMC Nephrol. 2018 Oct 20;19(1):280. doi: 10.1186/s12882-018-1093-0.
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