Schaub Jennifer A, Parikh Chirag R
Program of Applied Translational Research, Yale University, New Haven, CT, USA.
F1000Res. 2016 May 24;5. doi: 10.12688/f1000research.7998.1. eCollection 2016.
Acute kidney injury is strongly associated with increased mortality and other adverse outcomes. Medical researchers have intensively investigated novel biomarkers to predict short- and long-term outcomes of acute kidney injury in many patient care settings, such as cardiac surgery, intensive care units, heart failure, and transplant. Future research should focus on leveraging this relationship to improve enrollment for clinical trials of acute kidney injury.
急性肾损伤与死亡率增加及其他不良后果密切相关。医学研究人员已在许多患者护理场景中,如心脏手术、重症监护病房、心力衰竭和移植等,深入研究新型生物标志物以预测急性肾损伤的短期和长期后果。未来的研究应侧重于利用这种关系来改善急性肾损伤临床试验的入组情况。