Nayyar Ekta, Torres Julian A, Malvestutto Carlos D
Department of Infectious Diseases and Immunology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.
Case Rep Infect Dis. 2016;2016:5675036. doi: 10.1155/2016/5675036. Epub 2016 Apr 30.
Tuberculosis is a healthcare concern that affects millions of individuals around the globe. Coinfection with HIV has changed both the clinical presentation and the outcome of the disease dramatically in the last few decades. Extrapulmonary tuberculosis is seen more frequently in the immunocompromised host. An unusual case of gastric tuberculosis in an AIDS patient is reported here. A 49-year-old female with AIDS was admitted for fever and epigastric pain. A gastric submucosal abscess was observed on imaging and confirmed by biopsy showing numerous neutrophils and acid-fast bacilli. Aspirate grew Mycobacterium tuberculosis. This report highlights a very unusual presentation of tuberculosis in an immunodeficient patient. High clinical suspicion for opportunistic infections in unusual locations should be maintained in these patients presenting with clinical syndromes that do not respond to standard treatments. New diagnostic modalities facilitate accurate identification of these infections.
结核病是一个影响全球数百万人的医疗保健问题。在过去几十年中,与艾滋病毒的合并感染极大地改变了该疾病的临床表现和预后。肺外结核在免疫功能低下的宿主中更为常见。本文报告了一例艾滋病患者的罕见胃结核病例。一名49岁的艾滋病女性因发热和上腹部疼痛入院。影像学检查发现胃黏膜下脓肿,活检证实有大量中性粒细胞和抗酸杆菌。抽吸物培养出结核分枝杆菌。本报告强调了免疫缺陷患者中结核病的一种非常不寻常的表现。对于这些出现对标准治疗无反应的临床综合征的患者,应高度怀疑其在不寻常部位发生机会性感染。新的诊断方法有助于准确识别这些感染。