Stenqvist Charlotte, Madsen Christian Medom, Riis Troels, Jørgensen Henrik Løvendahl, Duus Benn Rønnow, Lauritzen Jes Bruun, van der Mark Susanne
Department of Orthopedic Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Geriatr Orthop Surg Rehabil. 2016 Jun;7(2):67-73. doi: 10.1177/2151458515625296. Epub 2016 Mar 2.
Orthogeriatric service has been shown to improve outcomes in patients with hip fracture. The purpose of this study is to evaluate the effect of orthogeriatrics at Bispebjerg University Hospital, Denmark. The primary outcome is mortality inhospital and after 1, 3, and 12 months for patients with hip fracture. The secondary outcome is mortality for home dwellers and nursing home inhabitants.
This is a retrospective clinical cohort study with an historic control group including all patients with hip fracture admitted from 2007 to 2011. Patients with hip fracture are registered in a local database, and data are retrieved retrospectively using the Danish Civil Registration Number.
We included 993 patients in the intervention group and 989 patients in the control group. A univariate analysis showed only significantly decreased mortality inhospital 6.3% vs 3.1% (P = .009) after orthogeriatrics. However, when adjusting for age, gender, and American Society of Anaesthesiologists (ASA) score in a multivariate analysis, including all patients with hip fracture, we find significantly reduced mortality inhospital (odds ratio [OR] 0.35), after 30 [OR 0.66] and 90 days [OR 0.72] and 1 year [OR 0.79]). When using a univariate analysis for home-dwelling patients, we found significantly reduced mortality inhospital (8.3-2.0%, P < .0001), after 30 days (12.2-6.8%, P = .004) and 90 days (20.5-13.0%, P = .002). One-year mortality was not significant. Patients from nursing homes had no significant decreasing mortality at any point of time in the univariate analysis.
We have shown significant decreases for inhospital, 30 day, 90 day, and 1-year mortality after implementation of orthogeriatric service at Bispebjerg Hospital when adjusting for age, gender, and ASA score. Future trials should include frail patients with other fracture types who can benefit from orthogeriatrics.
骨科老年医学服务已被证明可改善髋部骨折患者的治疗效果。本研究的目的是评估丹麦比斯珀比约格大学医院骨科老年医学的效果。主要结局是髋部骨折患者的住院死亡率以及1个月、3个月和12个月后的死亡率。次要结局是居家患者和养老院居民的死亡率。
这是一项回顾性临床队列研究,设有历史对照组,纳入了2007年至2011年期间收治的所有髋部骨折患者。髋部骨折患者登记在当地数据库中,使用丹麦民事登记号码进行回顾性数据检索。
我们纳入了干预组的993例患者和对照组的989例患者。单因素分析显示,骨科老年医学服务后仅住院死亡率显著降低,分别为6.3%和3.1%(P = .009)。然而,在多因素分析中对年龄、性别和美国麻醉医师协会(ASA)评分进行校正后,纳入所有髋部骨折患者,我们发现住院死亡率(优势比[OR] 0.35)、30天(OR 0.66)、90天(OR 0.72)和1年(OR 0.79)后均显著降低。对居家患者进行单因素分析时,我们发现住院死亡率显著降低(8.3 - 2.0%,P < .0001),30天后(12.2 - 6.8%,P = .004)和90天后(20.5 - 13.0%,P = .002)。1年死亡率无显著差异。在单因素分析中,养老院患者在任何时间点的死亡率均无显著下降。
在对年龄、性别和ASA评分进行校正后,我们发现比斯珀比约格医院实施骨科老年医学服务后,住院、30天、90天和1年死亡率均显著降低。未来的试验应纳入其他骨折类型的体弱患者,他们可能从骨科老年医学服务中受益。