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[阿尔茨海默病患者生活质量(QoL-AD)代理指标的内部一致性和结构效度——二次数据分析]

[Internal consistency and construct validity of the Quality of Life in Alzheimer's Disease (QoL-AD) proxy – a secondary data analysis].

作者信息

Hylla Jonas, Schwab Christian G G, Isfort Michael, Halek Margareta, Dichter Martin N

机构信息

1 Katholische Hochschule Nordrhein-Westfalen (KatHO NRW), Abteilung Köln.

2 Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Witten.

出版信息

Pflege. 2016 Jul;29(4):183-91. doi: 10.1024/1012-5302/a000494. Epub 2016 May 30.

DOI:10.1024/1012-5302/a000494
PMID:27239744
Abstract

Background: The maintenance and promotion of Quality of Life (QoL) of people with dementia is a major outcome in intervention studies and health care. The Quality of Life Alzheimer's Disease (QoL-AD) is an internationally recommended QoL measurement also available in German language. Until now, only a few results on the psychometric properties of the German QoL-AD were available. Objective: Evaluation of internal consistency and construct validity of the QoL-AD proxy. Method: A principal component analysis (secondary data analysis) of the 13 QoL-AD items was carried out based on the total sample of 234 people with dementia from nine nursing homes in Germany. Subsequently, the internal consistency of the identified factors was examined using Cronbach's alpha. Results: Two factors physical and mental health and social network were determined. Both factors explain 53 % of the total variance. The stability of both factors was validated in two sensitivity analyses. The internal consistency is good for both factors with a Cronbach's alpha of 0.88 (physical and mental health) and 0.75 (social network). Conclusion: The QoL-AD proxy allows the assessment of two relevant health-related QoL domains of people with dementia. However, in future studies especially the inter-rater reliability of the QoL-AD proxy has to be examined.

摘要

背景

维持和提高痴呆症患者的生活质量(QoL)是干预研究和医疗保健的主要成果。阿尔茨海默病生活质量量表(QoL-AD)是一项国际推荐的生活质量测量工具,也有德语版本。到目前为止,关于德语版QoL-AD心理测量特性的结果还很少。目的:评估QoL-AD代理版本的内部一致性和结构效度。方法:基于德国九家养老院234名痴呆症患者的总样本,对QoL-AD的13个项目进行主成分分析(二次数据分析)。随后,使用克朗巴赫α系数检验所识别因素的内部一致性。结果:确定了两个因素,即身心健康和社会网络。这两个因素解释了总方差的53%。在两项敏感性分析中验证了这两个因素的稳定性。两个因素的内部一致性都很好,克朗巴赫α系数分别为0.88(身心健康)和0.75(社会网络)。结论:QoL-AD代理版本能够评估痴呆症患者两个与健康相关的重要生活质量领域。然而,在未来的研究中,尤其需要检验QoL-AD代理版本的评分者间信度。

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