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德国生活质量-阿尔茨海默病量表(QoL-AD)自评量表的有效性和可靠性。

Validity and Reliability of the German Quality of Life-Alzheimer's Disease (QoL-AD) Self-Report Scale.

机构信息

Department of Geriatric Psychiatry and Psychotherapy, LVR-Hospital Cologne, Cologne, Germany.

Institute of Movement and Sport Gerontology, German Sport University Cologne, Cologne, Germany.

出版信息

J Alzheimers Dis. 2020;77(2):581-590. doi: 10.3233/JAD-200400.

Abstract

BACKGROUND

The Quality of Life-Alzheimer's Disease (QoL-AD) scale is a widely used measure of quality of life (QoL) in dementia. Although the instrument has been validated in several languages, the psychometric properties of the German self-report version have not yet been analyzed.

OBJECTIVE

This study examines the internal consistency, test-retest reliability, and construct validity of the German QoL-AD self-report scale.

METHODS

The sample included 30 patients suffering from mild to moderate Alzheimer's disease or vascular dementia (19 females; mean age 77.3 years; mean Mini-Mental State Examination (MMSE) score 19.7 points). To determine test-retest reliability, the QoL-AD self-report scale was re-administered four to seven days apart. For construct validity analysis, the Dementia Quality of Life instrument (DQoL), Geriatric Depression Scale (GDS), MMSE, and an adapted short form of the Neuropsychiatric Inventory (NPI) were used.

RESULTS

The German QoL-AD self-report scale shows an internal consistency of α= 0.79 and a test-retest reliability of r = 0.75 (p < 0.01). Regarding construct validity, there was a significant positive correlation between the total scores of the QoL-AD and DQoL (r = 0.47, p < 0.05). The analysis revealed no significant correlations with the GDS or the adapted NPI. No association could be observed between the QoL-AD and the MMSE (r = 0.01), confirming divergent validity.

CONCLUSION

The results indicate that the German QoL-AD self-report scale is a suitable instrument for assessing QoL in patients suffering from mild to moderate dementia, thus supporting its use in clinical practice and research.

摘要

背景

生活质量-阿尔茨海默病量表(QoL-AD)是一种广泛用于痴呆症患者生活质量(QoL)的测量工具。尽管该工具已在多种语言中得到验证,但德语自我报告版本的心理测量特性尚未得到分析。

目的

本研究旨在分析德国 QoL-AD 自我报告量表的内部一致性、重测信度和结构效度。

方法

该样本包括 30 名患有轻度至中度阿尔茨海默病或血管性痴呆的患者(19 名女性;平均年龄 77.3 岁;平均简易精神状态检查(MMSE)得分为 19.7 分)。为了确定重测信度,在相隔 4 至 7 天的时间内重新进行 QoL-AD 自我报告量表的测试。为了进行结构效度分析,使用了痴呆症生活质量量表(DQoL)、老年抑郁量表(GDS)、MMSE 和神经精神问卷(NPI)的简化版。

结果

德国 QoL-AD 自我报告量表的内部一致性为α=0.79,重测信度为 r=0.75(p<0.01)。在结构效度方面,QoL-AD 总分与 DQoL 总分呈显著正相关(r=0.47,p<0.05)。分析显示与 GDS 或改良的 NPI 无显著相关性。QoL-AD 与 MMSE 之间也没有关联(r=0.01),证实了它的区别效度。

结论

研究结果表明,德国 QoL-AD 自我报告量表是评估轻度至中度痴呆患者生活质量的一种合适工具,因此支持其在临床实践和研究中的应用。

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