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[脓疱型银屑病]

[Pustular psoriasis].

作者信息

Weisenseel P, Wilsmann-Theis D, Kahl C, Reich K, Mössner R

机构信息

SCIderm Clinical Research and Dermatologikum, Hamburg, Deutschland.

Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum Bonn, Bonn, Deutschland.

出版信息

Hautarzt. 2016 Jun;67(6):445-53. doi: 10.1007/s00105-016-3804-4.

Abstract

A number of pustular skin diseases share clinical, pathogenetic, and epidemiological aspects with plaque-type psoriasis, and their classification as a separate clinical entity or as a subtype of psoriasis remains controversial, which is also reflected in the multitude of their names. They include generalized pustular psoriasis with its subtypes, acrodermatitis continua suppurativa (Hallopeau), acute pustulosis palmopantaris, palmoplantar pustular psoriasis, and pustular variants of a mostly TNF-blocker triggered paradoxical psoriasiform dermatitis. In this article, the epidemiology, clinical picture, pathogenesis, genetics, and therapy of these pustular skin diseases are described.

摘要

许多脓疱性皮肤病在临床、发病机制和流行病学方面与斑块型银屑病有共同之处,将它们归类为一个独立的临床实体或银屑病的一个亚型仍存在争议,这也体现在它们众多的名称上。它们包括泛发性脓疱型银屑病及其亚型、连续性肢端皮炎(Hallopeau型)、急性掌跖脓疱病、掌跖脓疱型银屑病,以及主要由肿瘤坏死因子阻滞剂引发的矛盾性银屑病样皮炎的脓疱变体。本文描述了这些脓疱性皮肤病的流行病学、临床表现、发病机制、遗传学和治疗方法。

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