Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
J Mov Disord. 2016 May;9(2):55-62. doi: 10.14802/jmd.16014. Epub 2016 May 25.
Focal hand dystonia (FHD) is characterized by excessive and unwanted muscle activation in both the hand and arm resulting in impaired performance in particular tasks. Understanding the pathophysiology of FHD has progressed significantly for several decades and this has led to consideration of other potential therapies such as non-invasive brain stimulation (NIBS). A number of studies have been conducted to develop new therapy for FHD using transcranial magnetic stimulation and transcranial direct current stimulation. In this paper, we review previous studies and describe the potential therapeutic use of NIBS for FHD. We also discuss the future direction of NIBS to treat FHD.
局限性手部肌张力障碍(FHD)的特征是手部和手臂过度且不自主的肌肉活动,导致特定任务的表现受损。几十年来,FHD 的病理生理学研究取得了显著进展,这促使人们考虑其他潜在的治疗方法,如非侵入性脑刺激(NIBS)。已经进行了多项研究,以利用经颅磁刺激和经颅直流电刺激为 FHD 开发新的治疗方法。在本文中,我们回顾了以前的研究,并描述了 NIBS 治疗 FHD 的潜在治疗用途。我们还讨论了 NIBS 治疗 FHD 的未来方向。