Department of Chemistry, University of Oxford, Chemistry Research Laboratory, 12 Mansfield Rd, Oxford OX1 3TA, UK.
Nanotechnology. 2016 Jul 8;27(27):274003. doi: 10.1088/0957-4484/27/27/274003. Epub 2016 May 31.
The recent development of open-access optical microcavities opens up a number of intriguing possibilities in the realm of chemical sensing. We provide an overview of the different possible sensing modalities, with examples of refractive index sensing, optical absorption measurements, and optical tracking and trapping of nanoparticles. The extremely small mode volumes within an optical microcavity allow very small numbers of molecules to be probed: our current best detection limits for refractive index and absorption sensing are around 10(5) and 10(2) molecules, respectively, with scope for further improvements in the future.
最近开放式光学微腔的发展为化学传感领域开辟了许多有趣的可能性。我们提供了不同可能的传感模式的概述，包括折射率传感、光学吸收测量以及纳米粒子的光学跟踪和捕获。光学微腔中的极小模式体积允许探测非常少量的分子：我们目前在折射率和吸收传感方面的最佳检测极限分别约为 10^5 和 10^2 个分子，未来还有进一步提高的空间。
