Buse Judith, Enghardt Stephanie, Kirschbaum Clemens, Ehrlich Stefan, Roessner Veit
Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden , Dresden , Germany.
Department of Psychology, Technische Universität Dresden , Dresden , Germany.
Front Psychiatry. 2016 May 17;7:84. doi: 10.3389/fpsyt.2016.00084. eCollection 2016.
It has been suggested that psychosocial stress influences situational fluctuations of tic frequency. However, evidence from experimental studies is lacking. The current study investigated the effects of the Trier Social Stress Test (TSST-C) on tic frequency in 31 children and adolescents with tic disorders. A relaxation and a concentration situation served as control conditions. Patients were asked either to suppress their tics or to "tic freely." Physiological measures of stress were measured throughout the experiment. The TSST-C elicited a clear stress response with elevated levels of saliva cortisol, increased heart rate, and a larger number of skin conductance responses. During relaxation and concentration, the instruction to suppress tics reduced the number of tics, whereas during stress, the number of tics was low, regardless of the given instruction. Our study suggests that the stress might result in a situational decrease of tic frequency.
有观点认为，心理社会压力会影响抽动频率的情境波动。然而，缺乏来自实验研究的证据。本研究调查了特里尔社会应激测试（TSST-C）对31名患有抽动障碍的儿童和青少年抽动频率的影响。以放松和专注情境作为对照条件。要求患者要么抑制抽动，要么“自由抽动”。在整个实验过程中测量应激的生理指标。TSST-C引发了明显的应激反应，唾液皮质醇水平升高、心率加快以及皮肤电反应增多。在放松和专注期间，抑制抽动的指令减少了抽动次数，而在应激期间，无论给出何种指令，抽动次数都较少。我们的研究表明，应激可能导致抽动频率在情境中降低。
