J Acad Nutr Diet. 2016 Nov;116(11):1810-1816. doi: 10.1016/j.jand.2016.04.013. Epub 2016 May 28.
To date, it is unclear whether individuals with celiac disease following a gluten-free (GF) diet for several years have adequate intake of all recommended nutrients. Lack of a food frequency questionnaire (FFQ) for individuals with celiac disease could be partly responsible for this still-debated issue.
The aim of the study is to evaluate the performance of a modified European Prospective Investigation into Cancer and Nutrition (EPIC) FFQ in estimating nutrient and food intake in a celiac population.
In a cross-sectional study, the dietary habits of individuals with celiac disease were reported using a modified Italian EPIC FFQ and were compared to a 7-day weighed food record as a reference method.
PARTICIPANTS/SETTING: A total of 200 individuals with histologically confirmed celiac disease were enrolled in the study between October 2012 and August 2014 at the Center for Prevention and Diagnosis of Celiac Disease (Milan, Italy).
Nutrient and food category intake were calculated by 7-day weighed food record using an Italian food database integrated with the nutrient composition of 60 GF foods and the modified EPIC FFQ, in which 24 foods were substituted with GF foods comparable for energy and carbohydrate content.
An evaluation of the modified FFQ compared to 7-day weighed food record in assessing the reported intake of nutrient and food groups was conducted using Spearman's correlation coefficients and weighted κ.
One hundred individuals completed the study. The Spearman's correlation coefficients of FFQ and 7-day weighed food record ranged from .13 to .73 for nutrients and from .23 to .75 for food groups. A moderate agreement, which was defined as a weighted κ value of .40 to .60, was obtained for 30% of the analyzed nutrients, and 40% of the nutrients showed values between .30 and .40. The weighted κ exceeded .40 for 60% of the 15 analyzed food groups.
The modified EPIC FFQ demonstrated moderate congruence with a weighed food record in ranking individuals by dietary intakes, particularly food groups.
迄今为止，尚不清楚已经遵循无麸质（GF）饮食多年的乳糜泻患者是否摄入了所有推荐营养素。缺乏乳糜泻患者的食物频率问卷（FFQ）可能是导致这一仍有争议问题的部分原因。
本研究旨在评估改良的欧洲癌症与营养前瞻性调查（EPIC）FFQ 评估乳糜泻人群营养素和食物摄入量的性能。
在一项横断面研究中，使用改良的意大利 EPIC FFQ 报告乳糜泻患者的饮食习惯，并将其与 7 天称重食物记录作为参考方法进行比较。
参与者/设置：2012 年 10 月至 2014 年 8 月，在意大利米兰的乳糜泻疾病预防和诊断中心共纳入 200 例组织学确诊的乳糜泻患者。
使用意大利食物数据库和 60 种 GF 食物的营养素组成以及改良的 EPIC FFQ 计算 7 天称重食物记录中的营养素和食物类别摄入量，其中 24 种食物用能量和碳水化合物含量相当的 GF 食物替代。
使用 Spearman 相关系数和加权κ评估改良 FFQ 与 7 天称重食物记录在评估报告的营养素和食物组摄入量方面的差异。
100 名患者完成了研究。FFQ 和 7 天称重食物记录的 Spearman 相关系数范围为营养素 0.13 至 0.73，食物组 0.23 至 0.75。对于分析的营养素中有 30%获得了中度一致性，定义为加权κ值为 0.40 至 0.60，而 40%的营养素值在 0.30 至 0.40 之间。对于分析的 15 个食物组中的 60%，加权κ 值超过 0.40。
改良的 EPIC FFQ 在通过饮食摄入量对个体进行分类方面，特别是食物组方面，与称重食物记录具有中度一致性。
