Williams D F
Institute of Medical and Dental Bioengineering, University of Liverpool, UK.
J Biomed Eng. 1989 May;11(3):185-91. doi: 10.1016/0141-5425(89)90138-6.
Concepts of biocompatibility have changed radically in recent years. This paper describes these new concepts and the present knowledge of the components and mediators of biocompatibility and leads to the development of a model for the explanation and rationalization of these phenomena. Of particular importance is the question of the assessment or evaluation of biocompatibility. The paper concludes with comments on the need for a schedule of biocompatibility assessment procedures to take into account this new thinking.
近年来，生物相容性的概念发生了根本性的变化。本文描述了这些新概念以及生物相容性的组成部分和介质的现有知识，并得出了一个用于解释和合理化这些现象的模型。生物相容性评估的问题尤为重要。本文最后评论了制定生物相容性评估程序时间表以考虑这一新思路的必要性。
