Runnqvist Elin, Bonnard Mireille, Gauvin Hanna S, Attarian Shahram, Trébuchon Agnès, Hartsuiker Robert J, Alario F-Xavier
Aix-Marseille Université, CNRS, LPL UMR 7309, Aix-en-Provence, France.
Aix-Marseille Université, INSERM, INS UMR S 1106, Faculté de Médecine, Marseille, France.
Cortex. 2016 Aug;81:203-14. doi: 10.1016/j.cortex.2016.05.008. Epub 2016 May 21.
Some language processing theories propose that, just as for other somatic actions, self-monitoring of language production is achieved through internal modeling. The cerebellum is the proposed center of such internal modeling in motor control, and the right cerebellum has been linked to an increasing number of language functions, including predictive processing during comprehension. Relating these findings, we tested whether the right posterior cerebellum has a causal role for self-monitoring of speech errors. Participants received 1 Hz repetitive transcranial magnetic stimulation during 15 min to lobules Crus I and II in the right hemisphere, and, in counterbalanced orders, to the contralateral area in the left cerebellar hemisphere (control) in order to induce a temporary inactivation of one of these zones. Immediately afterwards, they engaged in a speech production task priming the production of speech errors. Language production was impaired after right compared to left hemisphere stimulation, a finding that provides evidence for a causal role of the cerebellum during language production. We interpreted this role in terms of internal modeling of upcoming speech through a verbal working memory process used to prevent errors.
一些语言处理理论认为，正如其他躯体动作一样，语言生成的自我监测是通过内部建模实现的。小脑被认为是运动控制中这种内部建模的中心，并且右小脑与越来越多的语言功能相关联，包括理解过程中的预测性处理。结合这些发现，我们测试了右后小脑在言语错误自我监测中是否具有因果作用。参与者在15分钟内接受1赫兹重复经颅磁刺激，刺激右侧半球的 Crus I和II小叶，并以平衡顺序刺激左小脑半球的对侧区域（对照），以诱导其中一个区域暂时失活。之后，他们立即参与一项言语生成任务，该任务会引发言语错误。与左侧半球刺激相比，右侧半球刺激后语言生成受损，这一发现为小脑在语言生成过程中的因果作用提供了证据。我们通过用于防止错误的言语工作记忆过程，将这一作用解释为对即将到来的言语的内部建模。
