Kuwano H, Matsuda H, Nagamatsu M, Inoue T, Ohno S, Mori M, Sugimachi K
Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
J Surg Oncol. 1989 Jun;41(2):77-80. doi: 10.1002/jso.2930410205.
A review of data on 548 patients with primary squamous cell carcinoma revealed that 24 (4.4%) had had gastrectomy. Although the interval of the gastrectomy due to peptic ulcer or gastric cancer and esophageal cancer was 13.4 +/- 7.9 and 5.8 +/- 4.2 years, respectively, this difference was thought to be due only to the occurrence of each disease. The incidence of the occurrence of the lower esophageal cancer after gastrectomy was 29.2%, not significantly higher than the 22.4% incidence of lower esophageal cancer in overall cases. Histopathological investigation of the 13 resected esophageal cancer tissues from gastrectomized patients revealed a mild esophagitis in some cases, with no significant histologic characteristics. Thus esophageal squamous cell carcinoma and previous gastrectomy may be incidentally related.
对548例原发性鳞状细胞癌患者的数据回顾显示,其中24例(4.4%)曾接受过胃切除术。尽管因消化性溃疡或胃癌及食管癌进行胃切除术的间隔时间分别为13.4±7.9年和5.8±4.2年,但这种差异被认为仅归因于每种疾病的发生情况。胃切除术后下食管癌的发生率为29.2%,并不显著高于总体病例中下食管癌22.4%的发生率。对13例胃切除患者切除的食管癌组织进行组织病理学检查发现,部分病例存在轻度食管炎,无明显组织学特征。因此,食管鳞状细胞癌与既往胃切除术可能存在偶然关联。