Tunkel D E, Loury M C, Fox C H, Johns M E
Department of Otolaryngology/Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Md.
Laryngoscope. 1989 Jun;99(6 Pt 1):590-5. doi: 10.1288/00005537-198906000-00005.
Bilateral enlargement of the parotid glands has been noted in five patients who are seropositive for antibody to the human immunodeficiency virus. A characteristic cystic appearance has been noted in these lesions on clinical and radiographic examination. A benign lymphoepithelial infiltrate with cystic degeneration is found in parotid specimens from these patients. The presence of human immunodeficiency virus ribonucleic acid in inflammatory cells infiltrating the parotid specimen was confirmed by an in situ hybridization technique. The clinical manifestations of sicca syndrome were not present nor were opportunistic infections diagnostic for the acquired immunodeficiency syndrome.
在五名人类免疫缺陷病毒抗体血清学阳性的患者中发现双侧腮腺肿大。临床和影像学检查发现这些病变具有特征性的囊性外观。在这些患者的腮腺标本中发现了伴有囊性变的良性淋巴上皮浸润。通过原位杂交技术证实了浸润腮腺标本的炎性细胞中存在人类免疫缺陷病毒核糖核酸。患者没有干燥综合征的临床表现，也没有获得性免疫缺陷综合征的机会性感染诊断依据。
