Parikh Shilpa, Sharma Sheetal, Shah Jigna S
Oral medicine and radiology department, Government Dental College, Ahmedabad, India.
Oral medicine and radiology department, CDER, AIIMS, New Delhi, India.
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5342-5346. doi: 10.1007/s12070-021-02511-1. Epub 2021 Apr 10.
Kimura disease (KD) is a chronic inflammatory lymphoproliferative disorder of unknown etiology and unsure pathogenesis. It primarily involves the head and neck region, presenting as an asymptomatic unilateral soft-tissue mass in the head and neck, frequently involving subcutaneous tissues, major salivary gland, lymph nodes. Peripheral blood eosinophilia, elevated serum immunoglobulin E (IgE) levels, and the microscopically lymphoid proliferation with eosinophilic infiltration are the characteristic features. We report a case of KD in a 22-year-old Indian male who presented with an asymptomatic parotid gland enlargement with lymphadenopathy. The clinical presentation was suggestive of the benign lesion but histopathology, as well as microscopic findings, allowed us to make a definitive diagnosis of KD. The patient was treated with steroids and antihistamine and showed no recurrence on follow-up.
木村病（KD）是一种病因不明、发病机制尚不清楚的慢性炎症性淋巴增殖性疾病。它主要累及头颈部区域，表现为头颈部无症状的单侧软组织肿块，常累及皮下组织、大唾液腺和淋巴结。外周血嗜酸性粒细胞增多、血清免疫球蛋白E（IgE）水平升高以及显微镜下的淋巴样增生伴嗜酸性粒细胞浸润是其特征性表现。我们报告一例22岁印度男性木村病患者，该患者表现为无症状的腮腺肿大伴淋巴结病。临床表现提示为良性病变，但组织病理学及显微镜检查结果使我们能够明确诊断为木村病。该患者接受了类固醇和抗组胺药治疗，随访期间未复发。
