Hale Daniel E, Wyatt Sharon B, Buka Stephen, Cherry Debra, Cislo Kendall K, Dudley Donald J, McElfish Pearl Anna, Norman Gwendolyn S, Reynolds Simone A, Siega-Riz Anna Maria, Wadlinger Sandra, Walker Cheryl K, Robbins James M
Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas;
School of Nursing, University of Mississippi Medical Center, University of Mississippi, Jackson, Mississippi;
Pediatrics. 2016 Jun;137 Suppl 4(Suppl 4):S239-47. doi: 10.1542/peds.2015-4410E.
In 2009, the National Children's Study (NCS) Vanguard Study tested the feasibility of household-based recruitment and participant enrollment using a birth-rate probability sample. In 2010, the NCS Program Office launched 3 additional recruitment approaches. We tested whether provider-based recruitment could improve recruitment outcomes compared with household-based recruitment.
The NCS aimed to recruit 18- to 49-year-old women who were pregnant or at risk for becoming pregnant who lived in designated geographic segments within primary sampling units, generally counties. Using provider-based recruitment, 10 study centers engaged providers to enroll eligible participants at their practice. Recruitment models used different levels of provider engagement (full, intermediate, information-only).
The percentage of eligible women per county ranged from 1.5% to 57.3%. Across the centers, 3371 potential participants were approached for screening, 3459 (92%) were screened and 1479 were eligible (43%). Of those 1181 (80.0%) gave consent and 1008 (94%) were retained until delivery. Recruited participants were generally representative of the county population.
Provider-based recruitment was successful in recruiting NCS participants. Challenges included time-intensity of engaging the clinical practices, differential willingness of providers to participate, and necessary reliance on providers for participant identification. The vast majority of practices cooperated to some degree. Recruitment from obstetric practices is an effective means of obtaining a representative sample.
2009年,国家儿童研究(NCS)先锋研究使用出生率概率样本测试了基于家庭招募和参与者入组的可行性。2010年,NCS项目办公室推出了另外3种招募方法。我们测试了与基于家庭的招募相比,基于医疗服务提供者的招募是否能改善招募结果。
NCS旨在招募居住在主要抽样单位(通常为县)内指定地理区域的18至49岁怀孕或有怀孕风险的女性。通过基于医疗服务提供者的招募,10个研究中心让医疗服务提供者在其诊所为符合条件的参与者进行登记。招募模式采用了不同程度的医疗服务提供者参与度(全面、中等、仅提供信息)。
每个县符合条件的女性比例在1.5%至57.3%之间。在各个中心,共接触了3371名潜在参与者进行筛查,3459名(92%)接受了筛查,1479名符合条件(43%)。其中1181名(80.0%)给予了同意,1008名(94%)被保留至分娩。招募的参与者总体上代表了该县人口。
基于医疗服务提供者的招募成功招募到了NCS参与者。挑战包括参与临床实践的时间强度、医疗服务提供者参与意愿的差异以及对医疗服务提供者识别参与者的必要依赖。绝大多数诊所都在一定程度上进行了合作。从产科诊所招募是获得代表性样本的有效手段。