Westat, 1600 Research Blvd., Rockville, MD 20850, USA.
Stat Med. 2010 Jun 15;29(13):1368-76. doi: 10.1002/sim.3891.
The National Children's Study is a national household probability sample designed to identify 100,000 children at birth and follow the sampled children for 21 years. Data from the study will support examining numerous hypotheses concerning genetic and environmental effects on the health and development of children. The goals of the study present substantial challenges. For example, the need for preconception, prenatal, and postnatal data requires identifying women in the early stages of pregnancy, the collection of many types of data, and the retention of the children over time. In this paper, we give an overview of the sample design used in a pilot study called the Vanguard Study, and highlight the approaches used to address these challenges. We will also describe the rationale for the sampling choices made at each stage, the unique organizational structure of the NCS and issues we expect to face during implementation.
国家儿童研究是一个全国性的家庭概率抽样调查，旨在在出生时确定 10 万名儿童，并对抽样儿童进行 21 年的跟踪。该研究的数据将支持对许多关于遗传和环境对儿童健康和发育影响的假设进行检验。该研究的目标提出了重大挑战。例如，需要在受孕前、孕期和产后收集数据，这就需要在早期妊娠阶段确定妇女，收集多种类型的数据，并长期保留儿童。在本文中，我们将概述一个名为先锋研究的试点研究中使用的样本设计，并重点介绍解决这些挑战的方法。我们还将描述在每个阶段进行抽样选择的基本原理、NCS 的独特组织结构以及我们在实施过程中预计会面临的问题。
