Jilka Robert L
Center for Osteoporosis and Metabolic Bone Diseases, Division of Endocrinology and Metabolism, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
J Bone Miner Res. 2016 Jul;31(7):1317-9. doi: 10.1002/jbmr.2881.
Reproducibility of research findings is the hallmark of scientific advance. However, the recently noted lack of reproducibility and transparency of published research using animal models of human biology and disease has alarmed funders, scientists, and the public. Improved reporting of methodology and better use of statistical tools are needed to enhance the quality and utility of published research. Reporting guidelines like Animal Research: Reporting In Vivo Experiments (ARRIVE) have been devised to achieve these goals, but most biomedical research journals, including the JBMR, have not been able to obtain high compliance. Cooperative efforts among authors, reviewers and editors-empowered by increased awareness of their responsibilities, and enabled by user-friendly guidelines-are needed to solve this problem. © 2016 American Society for Bone and Mineral Research.
研究结果的可重复性是科学进步的标志。然而，最近注意到使用人类生物学和疾病动物模型的已发表研究缺乏可重复性和透明度，这引起了资助者、科学家和公众的警觉。需要改进方法报告并更好地使用统计工具，以提高已发表研究的质量和实用性。为实现这些目标已制定了诸如《动物研究：体内实验报告》（ARRIVE）等报告指南，但包括《骨与矿物质研究杂志》（JBMR）在内的大多数生物医学研究期刊都未能实现高合规性。需要作者、审稿人和编辑之间的合作努力——通过增强对其责任的认识，并借助用户友好的指南来实现——以解决这一问题。© 2016美国骨与矿物质研究学会。
