阿昔洛韦用于儿童疱疹性龈口炎

Acyclovir for herpetic gingivostomatitis in children.

作者信息

Goldman Ran D

出版信息

Can Fam Physician. 2016 May;62(5):403-4.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4865337/

Abstract

QUESTION

Every year I see preschool children with gingivostomatitis. There seems to be quite a substantial burden of illness with this condition. Because it is caused by herpes simplex virus type 1, should I prescribe antiherpetic therapy with oral acyclovir?

ANSWER

While most children with primary gingivostomatitis will be asymptomatic, some will experience considerable pain and discomfort and are at risk of dehydration. There are no large, well designed studies to clearly determine appropriate therapy for all children. Based on a single randomized study, treatment should be started only within the first 72 hours of symptom onset if substantial pain or dehydration are documented.

摘要

问题

每年我都会见到患有龈口炎的学龄前儿童。这种疾病似乎带来了相当大的疾病负担。由于它是由1型单纯疱疹病毒引起的，我是否应该开口服阿昔洛韦进行抗疱疹治疗呢？

答案

虽然大多数原发性龈口炎患儿无症状，但有些患儿会经历相当大的疼痛和不适，并有脱水风险。目前尚无大型、设计良好的研究来明确确定针对所有儿童的适当治疗方法。根据一项单一的随机研究，如果有明显疼痛或脱水记录，仅应在症状出现的头72小时内开始治疗。

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