Nguyen Emily P, Daeneke Torben, Zhuiykov Serge, Kalantar-Zadeh Kourosh
School of Electrical and Computer Engineering, RMIT University, Melbourne, Victoria, Australia.
Division of Materials Science and Engineering, CSIRO, Clayton, Victoria, Australia.
Curr Protoc Chem Biol. 2016 Jun 2;8(2):97-108. doi: 10.1002/cpch.3.
Known to possess distinctive properties that differ greatly from their bulk form, layered two-dimensional materials have been extensively studied and incorporated into many versatile applications ranging from optoelectronics to sensors. For biomedical research, two-dimensional transition metal dichalcogenides (2D TMDs) have garnered much interest as they have been shown to exhibit relatively low toxicity, high stability in aqueous environments, and the ability to adhere to biological materials such as proteins. These materials are promising candidates, demonstrating potential applications in biosensing, cell imaging, diagnostics, and therapeutics. Preparation and exfoliation of 2D TMDs play an important part in these various applications as their properties are heavily dependent on the number of layers and lateral size. Described in this article are protocols for the liquid exfoliation of 2D TMDs from their bulk materials. Additional protocols are also provided for functionalizing or modifying the surface of the exfoliated 2D TMDs. © 2016 by John Wiley & Sons, Inc.
已知层状二维材料具有与它们的块状形式有很大不同的独特性质，因此已被广泛研究并应用于从光电子学到传感器等许多通用领域。在生物医学研究中，二维过渡金属二硫属化物（2D TMDs）已引起了广泛关注，因为它们已被证明具有相对较低的毒性、在水环境中的高稳定性以及粘附于蛋白质等生物材料的能力。这些材料是很有前途的候选物，在生物传感、细胞成像、诊断和治疗等方面展示出潜在应用。二维过渡金属二硫属化物的制备和剥离在这些不同的应用中起着重要作用，因为它们的性质在很大程度上取决于层数和横向尺寸。本文描述了从块状材料中对二维过渡金属二硫属化物进行液体剥离的方案。还提供了用于对剥离后的二维过渡金属二硫属化物表面进行功能化或修饰的其他方案。© 2016 约翰威立国际出版公司。
