Skotnicki Piotr, Sas-Korczynska Beata, Strzepek Lukasz, Jakubowicz Jerzy, Blecharz Pawel, Reinfuss Marian, Walasek Tomasz
Department of Surgical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Department of Clinical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Breast J. 2016 Sep;22(5):529-34. doi: 10.1111/tbj.12621. Epub 2016 Jun 4.
Mucinous breast carcinoma (MBC) carcinoma represents approximately 1-6% of all malignant breast carcinoma and is divided into pure (PMBC) and mixed (MMBC) subtypes. This study presents the comparison of clinical characteristics and treatment results in 70 patients with PMBC and 40 patients with MMBC, treated at a single institution during 25 years. Performed analyses showed that only nodal status was different in both subtypes. Patients with MMBC showed a significantly higher incidence of axillary nodal metastases in comparison to PMBC (25% versus 10%, respectively). Instead, the 10-year disease-free survival rate was significant higher in PMBC than MMBC (85.7% versus 65%, p < 0.02, test log rank). Authors own observations and data from literature proved that MMBC should be considered as subtypes of mucinous breast cancer.
黏液性乳腺癌(MBC)约占所有恶性乳腺癌的1%-6%,分为纯黏液性乳腺癌(PMBC)和混合性黏液性乳腺癌(MMBC)亚型。本研究比较了25年间在同一机构接受治疗的70例PMBC患者和40例MMBC患者的临床特征及治疗结果。分析表明,两种亚型仅在淋巴结状态上存在差异。与PMBC相比,MMBC患者腋窝淋巴结转移发生率显著更高(分别为25%和10%)。相反,PMBC的10年无病生存率显著高于MMBC(85.7%对65%,p<0.02,对数秩检验)。作者自己的观察结果和文献数据证明,MMBC应被视为黏液性乳腺癌的亚型。