从人类粪便中分离出的肠球菌的遗传模式和抗生素耐药性谱的时间变异性

Nishiyama Masateru, Shimauchi Hidetaka, Suzuki Yoshihiro

Department of Environment and Resource Science, Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki.

Microbes Environ. 2016 Jun 25;31(2):182-5. doi: 10.1264/jsme2.ME15158. Epub 2016 Jun 3.

Temporal variabilities in the genetic patterns and antibiotic resistance profiles of enterococci were monitored over a 7-month period. Enterococcus faecalis isolates (103 strains) collected from feces showed only one genetic pattern and antibiotic resistance profile within 0 d and 30 d. In contrast, after 60 d and 90 d, the genetic patterns and antibiotic resistance profiles of all E. faecalis isolates (8 strains) clearly differed within 30 d. These results indicate that the genetic patterns and antibiotic resistance profiles of E. faecalis in human feces changed to completely dissimilar patterns between 1 and 2 months.

在7个月的时间里监测了肠球菌遗传模式和抗生素耐药性谱的时间变异性。从粪便中收集的粪肠球菌分离株（103株）在0天至30天内仅表现出一种遗传模式和抗生素耐药性谱。相比之下，在60天和90天后，所有粪肠球菌分离株（8株）的遗传模式和抗生素耐药性谱在30天内明显不同。这些结果表明，人类粪便中粪肠球菌的遗传模式和抗生素耐药性谱在1至2个月内转变为完全不同的模式。