Hansen T, Weckesser M, Schäfers M, Gunnemann A
Institut für Pathologie, Klinikum Lippe GmbH, Röntgenstraße 18, 32756, Detmold, Deutschland.
Klinik für Nuklearmedizin, Universitätsklinikum Münster, Münster, Deutschland.
Urologe A. 2017 Jan;56(1):50-53. doi: 10.1007/s00120-016-0130-5.
We report on the case of an 81-year-old man suffering from prostate cancer for several years. In recent months, PSA levels increased, and Ga-PSMA-PET-CT (PSMA: prostate-specific membrane antigen) imaging demonstrated suspicious lesions in the paravesical area and an umbilical tumor mass. Local excision was performed. Histologically, the tumor mass was diagnosed as metastasis of the prostate cancer, which is also designated as Sister Mary Joseph's nodule. Umbilical metastases of primary prostate cancer are extremely rare; however, they are of clinical importance since they are commonly associated with tumor progress and with a particularly poor prognosis.
我们报告了一例患有前列腺癌数年的81岁男性病例。近几个月来，前列腺特异性抗原（PSA）水平升高，镓-前列腺特异性膜抗原（PSMA）-正电子发射断层扫描-计算机断层扫描（Ga-PSMA-PET-CT）成像显示膀胱旁区域有可疑病变以及脐部肿瘤肿块。进行了局部切除。组织学检查显示，该肿瘤肿块被诊断为前列腺癌转移，也被称为玛丽·约瑟夫修女结节。原发性前列腺癌的脐部转移极为罕见；然而，它们具有临床重要性，因为它们通常与肿瘤进展以及特别差的预后相关。
