Al-Daghri N M, Aljohani N J, Al-Attas O S, Al-Saleh Y, Alnaami A M, Sabico S, Amer O E, Alharbi M, Kumar S, Alokail M S
Biomarkers Research Program Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Prince Mutaib Chair for Biomarkers of Osteoporosis, King Saud University, Riyadh, Saudi Arabia.
Child Care Health Dev. 2016 Sep;42(5):652-7. doi: 10.1111/cch.12361. Epub 2016 Jun 7.
We aimed to compare the prevalence of childhood obesity and other cardiometabolic risk factors from two independent cohorts (2008 and 2013) in Riyadh, Saudi Arabia.
A total of 4549 adolescents aged 12-18 years [2454 boys, 2095 girls], taken from two independent cohorts, 5 years apart (2008 and 2013), were included. Anthropometrics were measured, and fasting blood samples were taken to ascertain glucose and lipid profile.
The overall prevalence of obesity was significantly higher in 2013 [15.3 (95% confidence interval 13.7-16.9)] than 2008 [12.6 (11.3-13.9)] (P = 0.012). Stratified by sex, the prevalence of obesity among boys was significantly higher in 2013 than 2008 [2008 = 12.0 (10.3-13.7) versus 2013 = 17.4 (15.1-19.7); P < 0.001]. The age groups 13 and 15 years had a significantly higher mean triglycerides in 2013 than 2008 (P-values 0.003 and <0.001, respectively) and lower mean HDL-cholesterol also in the 13 years old age group (P < 0.001).
The prevalence of childhood obesity in Saudi Arabia has increased in particular age groups (13-15 years) during a 5-year span. Special attention is warranted in these vulnerable age groups, particularly in boys, as cardiometabolic risk factors appear to worsen.
我们旨在比较沙特阿拉伯利雅得两个独立队列（2008年和2013年）中儿童肥胖及其他心血管代谢危险因素的患病率。
纳入了来自两个独立队列、间隔5年（2008年和2013年）的共4549名12至18岁青少年[2454名男孩，2095名女孩]。测量了人体测量学指标，并采集空腹血样以确定血糖和血脂情况。
2013年肥胖的总体患病率[15.3（95%置信区间13.7 - 16.9）]显著高于2008年[12.6（11.3 - 13.9）]（P = 0.012）。按性别分层，2013年男孩中的肥胖患病率显著高于2008年[2008年 = 12.0（10.3 - 13.7），2013年 = 17.4（15.1 - 19.7）；P < 0.001]。13岁和15岁年龄组在2013年的平均甘油三酯水平显著高于2008年（P值分别为0.003和<0.001），13岁年龄组的平均高密度脂蛋白胆固醇水平也较低（P < 0.001）。
在5年期间，沙特阿拉伯特定年龄组（13 - 15岁）的儿童肥胖患病率有所上升。鉴于心血管代谢危险因素似乎有所恶化，这些易患群体，尤其是男孩，应予以特别关注。
