Hukkanen V, Hakkarainen K, Leinikki P, Hyypiä T
Department of Virology, University of Turku, Finland.
Scand J Infect Dis. 1989;21(2):133-7. doi: 10.3109/00365548909039959.
This study compares the presence of hepatitis B virus (HBV) DNA and HBV e antigen in sera positive for IgM antibody to HBV core antigen. Of the 31 sera included in the study, 14 were HBV DNA positive. Eight sera were positive for HBV DNA but negative for HBeAg and 3 sera were negative for HBV DNA but positive for HBeAg. The HBV DNA positive specimens included also 3 HBsAg negative sera. The importance of the level of the anti HBc IgM antibody is discussed.
本研究比较了乙肝核心抗原IgM抗体阳性血清中乙肝病毒(HBV)DNA和乙肝e抗原的存在情况。在该研究纳入的31份血清中,14份HBV DNA呈阳性。8份血清HBV DNA阳性但HBeAg阴性,3份血清HBV DNA阴性但HBeAg阳性。HBV DNA阳性标本中还包括3份HBsAg阴性血清。文中讨论了抗HBc IgM抗体水平的重要性。