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高血压患者中心血管行为危险因素与血压的聚类分析:一项中国全国代表性调查

Clustering of cardiovascular behavioral risk factors and blood pressure among people diagnosed with hypertension: a nationally representative survey in China.

作者信息

Li Yichong, Feng Xiaoqi, Zhang Mei, Zhou Maigeng, Wang Ning, Wang Limin

机构信息

National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

School of Health and Society, University of Wollongong, Australia.

出版信息

Sci Rep. 2016 Jun 9;6:27627. doi: 10.1038/srep27627.

Abstract

This study aimed to examine association between the number of behavioral risk factors and blood pressure (BP) level among a nationally representative sample of Chinese people diagnosed with hypertension. A total of 31,694 respondents aged 18+ years with diagnosed hypertension were extracted from the 2013-2014 China Chronic Disease and Risk Factor Surveillance. BP of each respondent was classified into six levels according to criteria in 2007 Guidelines for the Management of Arterial Hypertension. Information for smoking, alcohol drinking, fruit and vegetables consumption, physical inactivity, and overweight and obesity were obtained. The average number of risk factors was determined by BP level to explore potential risk factor clustering. Ten generalized proportional odds models were used to examine association between clustering of behavioral risk factors and BP level. A clear gradient between the number of behavioral risk factors and BP level was observed for men and women (P < 0.05 for both genders). BP level for men and women was much likely to upgrade as number of risk factors accumulated (P < 0.01 for 10 models). Behavioral modifications may decrease BP, and combinations of two or more behavioral interventions could potentially result in even better BP management among people diagnosed with hypertension.

摘要

本研究旨在调查在中国具有全国代表性的高血压患者样本中,行为危险因素数量与血压(BP)水平之间的关联。从2013 - 2014年中国慢性病与危险因素监测中提取了总共31694名年龄在18岁及以上的确诊高血压患者。根据2007年《动脉高血压管理指南》的标准,将每位受访者的血压分为六个等级。获取了吸烟、饮酒、水果和蔬菜摄入量、身体活动不足以及超重和肥胖方面的信息。通过血压水平确定危险因素的平均数量,以探索潜在的危险因素聚集情况。使用十个广义比例优势模型来研究行为危险因素聚集与血压水平之间的关联。男性和女性的行为危险因素数量与血压水平之间均观察到明显的梯度(男女P均<0.05)。随着危险因素数量的累积,男性和女性的血压水平更有可能升高(10个模型的P均<0.01)。行为改变可能会降低血压,对于确诊高血压的患者,两种或更多行为干预措施的组合可能会带来更好的血压管理效果。

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