影响恒河猴（猕猴属）脱发和毛发皮质醇的因素。
Factors influencing alopecia and hair cortisol in rhesus macaques (Macaca mulatta).
作者信息
Lutz Corrine K, Coleman Kris, Worlein Julie M, Kroeker Rose, Menard Mark T, Rosenberg Kendra, Meyer Jerrold S, Novak Melinda A
机构信息
Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Oregon National Primate Research Center, Beaverton, OR, USA.
出版信息
J Med Primatol. 2016 Aug;45(4):180-8. doi: 10.1111/jmp.12220. Epub 2016 Jun 10.
BACKGROUND
Alopecia can occur in captive non-human primates, but its etiology is poorly understood. The purpose of this study was to assess alopecia and hair cortisol in rhesus monkeys and to identify the potential risk factors.
METHODS
Subjects were 117 rhesus monkeys at two National Primate Research Centers. Photographs and hair samples were obtained during routine physicals. Photographs were analyzed using Image J software to calculate hair loss, and hair samples were assayed for cortisol.
RESULTS
Age, days singly housed, and their interactions contributed to the alopecia model for both facilities. Sex and location changes contributed to the hair cortisol model for Facility 1; sedations contributed for Facility 2. Alopecia and hair cortisol were associated at Facility 1.
CONCLUSIONS
Captive management practices can affect alopecia and hair cortisol. However, there are facility differences in the relationship between alopecia and hair cortisol and in the effect of intrinsic variables and management procedures.
背景
圈养的非人灵长类动物会出现脱发，但对其病因了解甚少。本研究的目的是评估恒河猴的脱发情况和毛发皮质醇水平，并确定潜在的风险因素。
方法
研究对象为两个国家灵长类动物研究中心的117只恒河猴。在常规体检期间获取照片和毛发样本。使用Image J软件分析照片以计算脱发情况，并对毛发样本进行皮质醇检测。
结果
年龄、单独饲养天数及其相互作用对两个研究中心的脱发模型均有影响。性别和位置变化对研究中心1的毛发皮质醇模型有影响；镇静对研究中心2有影响。研究中心1的脱发与毛发皮质醇有关。
结论
圈养管理方式会影响脱发和毛发皮质醇水平。然而，脱发与毛发皮质醇之间的关系以及内在变量和管理程序的影响在不同研究中心存在差异。
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