Population and Behavioral Health Services, California National Primate Research Center, Davis, California, USA.
Division of Veterinary Medicine, Tulane National Primate Research Center, Covington, Louisiana, USA.
Am J Primatol. 2022 Jun;84(6):e23378. doi: 10.1002/ajp.23378. Epub 2022 Apr 1.
The social setting of animal subjects in the research environment has known effects on a variety of dependent measures used in biomedical research. Proper evaluation of the robustness of published research is dependent upon transparent, detailed, and accurate reporting of research methods, including the animals' social housing conditions. However, to date, most research articles utilizing nonhuman primates (NHPs) provide only partial data on this topic, hampering transparency, and reproducibility. Therefore, we call for the inclusion of information pertaining to the social aspects of the animals' housing conditions in publications involving NHPs to improve transparency. We argue that including this information in scientific publications is crucial for the interpretation of research findings in the appropriate context and for understanding unexplained variability in study findings. Finally, the inclusion of this information in publications will additionally familiarize scientists with how other researchers conducting similar studies are housing their animals and will encourage them to consider the implications of various housing conditions on their research outcomes.
动物实验对象的社会环境对生物医学研究中使用的各种因变量有已知的影响。对已发表研究的稳健性进行正确评估,取决于对研究方法的透明、详细和准确报告,包括动物的社会居住条件。然而,迄今为止,大多数使用非人类灵长类动物(NHP)的研究文章仅提供了该主题的部分数据,这阻碍了透明度和可重复性。因此,我们呼吁在涉及 NHP 的出版物中纳入与动物居住条件的社会方面有关的信息,以提高透明度。我们认为,在科学出版物中纳入这些信息对于在适当的背景下解释研究结果以及理解研究结果中无法解释的变异性至关重要。最后,在出版物中纳入这些信息将使科学家们更加了解其他研究人员如何饲养他们的动物,并鼓励他们考虑各种饲养条件对其研究结果的影响。