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糖皮质激素对过敏反应中类前列腺素物质释放的影响。

Effect of glucocorticosteroids on the release of prostaglandin-like substances in anaphylaxis.

作者信息

Gryglewski R J, Korbut R, Grodzińska L, Dembinska-Kieć A

出版信息

Agents Actions Suppl. 1977;2:67-76. doi: 10.1007/978-3-0348-7177-8_6.

Abstract

During anaphylactic reactions there are released thromboxane A2 and/or prostaglandin-like substances from perfused guinea pig lungs and from incubated fragments of guinea pig mesentery. Prostaglandin-like substances appear also in mixed venous blood of anaesthetized cats following an intravenous injection of rabbit blood. These release reactions are reduced or abolished both by indomethacin and by hydrocortisone.

摘要

在过敏反应期间,豚鼠灌注肺和豚鼠肠系膜孵育片段会释放血栓素A2和/或类前列腺素物质。静脉注射兔血后,麻醉猫的混合静脉血中也会出现类前列腺素物质。吲哚美辛和氢化可的松均可降低或消除这些释放反应。

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