Guo Kai-Min, Liu Yang, Zhong Yan-Ping, Wang Hong-Liang
Department of Andrology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Mol Clin Oncol. 2016 Jun;4(6):983-985. doi: 10.3892/mco.2016.829. Epub 2016 Mar 22.
Germ cell tumors account for 98% of all testicular malignancies. Delays in seeking treatment are unfortunately common and may lead to metastatic spread. The present study reported a case of a 24-year-old man with a giant 12×10 cm left inguinal mass and a left neck mass that had grown rapidly during recent months. Computed tomography confirmed that the mass measured 12.1×9.4 cm and was a left undescended testicle malignancy, and also revealed widespread metastasis to the liver and a large retroperitoneal mass (12.6×8.2 cm). Immunohistochemical staining confirmed seminoma. The patient was treated with chemotherapy with the VIP protocol (cisplatin, etoposide and ifosfamide). Following courses of chemotherapy, the patient received complete clinical remission and was disease-free at the 6 month follow-up.
生殖细胞肿瘤占所有睾丸恶性肿瘤的98%。不幸的是，延迟就医的情况很常见，可能会导致转移扩散。本研究报告了一例24岁男性病例，其左腹股沟有一个巨大的12×10 cm肿块，左颈部肿块在最近几个月迅速增大。计算机断层扫描证实该肿块大小为12.1×9.4 cm，是左侧隐睾恶性肿瘤，还显示有广泛的肝脏转移和一个巨大的腹膜后肿块（12.6×8.2 cm）。免疫组化染色确诊为精原细胞瘤。该患者接受了VIP方案（顺铂、依托泊苷和异环磷酰胺）化疗。经过几个疗程的化疗后，患者实现了完全临床缓解，在6个月的随访中无疾病复发。
