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颈部精原细胞瘤的结节样表现:1例罕见病例报告

Nodular expression of seminoma in the neck: An unusual case presentation.

作者信息

Crawford Charles K, Yasrab Mohammad, Fishman Elliot K

机构信息

Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Radiol Case Rep. 2024 Nov 30;20(2):1124-1129. doi: 10.1016/j.radcr.2024.11.020. eCollection 2025 Feb.

DOI:10.1016/j.radcr.2024.11.020
PMID:39691761
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650144/
Abstract

Seminoma is a malignant germ cell tumor that primarily develops in the testis but can occur in other extragonadal areas, most commonly the mediastinum and retroperitoneum. While generally offering a favorable prognosis, seminomas can sometimes clinically present with misleading characteristics resulting in delayed diagnosis. In this article, we report the case of a 31-year-old male diagnosed with grade IIIC intermediate risk testicular seminoma cTxN3M1bSx, who presented initially with a palpable cervical mass. We focus on the use of radiological modalities for an optimized diagnosis by coordinating our imaging with pathological findings and clinical presentation.

摘要

精原细胞瘤是一种恶性生殖细胞肿瘤,主要发生于睾丸,但也可出现在其他性腺外区域,最常见于纵隔和腹膜后。虽然精原细胞瘤总体预后良好,但有时在临床上会表现出具有误导性的特征,导致诊断延迟。在本文中,我们报告了一例31岁男性患者,诊断为IIIC期中间风险睾丸精原细胞瘤cTxN3M1bSx,该患者最初表现为可触及的颈部肿块。我们通过将影像学检查结果与病理结果及临床表现相结合,重点探讨了利用放射学检查手段进行优化诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11650144/a25bcf6ee33a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11650144/a42a2c318daa/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11650144/a25bcf6ee33a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11650144/a42a2c318daa/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11650144/a25bcf6ee33a/gr2.jpg

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本文引用的文献

1
Metastatic seminoma presenting as neck and axillary lymphadenopathy in an elderly man.一名老年男性转移性精原细胞瘤表现为颈部和腋窝淋巴结病。
Proc (Bayl Univ Med Cent). 2023 Jan 24;36(3):395-397. doi: 10.1080/08998280.2023.2167184. eCollection 2023.
2
Contrast-enhanced ultrasound in the diagnosis of a solitary neck mass: a case report of metastatic seminoma.超声造影在单发颈部肿块诊断中的应用:一例转移性精原细胞瘤病例报告。
J Int Med Res. 2022 Nov;50(11):3000605221135482. doi: 10.1177/03000605221135482.
3
Supraclavicular left neck mass: an unusual presentation of metastatic testicular cancer in two older men.
左锁骨上颈部肿块:两名老年男性转移性睾丸癌的不寻常表现。
BMJ Case Rep. 2020 Apr 22;13(4):e233368. doi: 10.1136/bcr-2019-233368.
4
Mediastinal seminoma presenting as a neck mass falsely diagnosed as anaplastic thyroid carcinoma: A case report.表现为颈部肿块且被误诊为间变性甲状腺癌的纵隔精原细胞瘤:一例报告
Diagn Cytopathol. 2019 Apr;47(4):334-336. doi: 10.1002/dc.24090. Epub 2018 Nov 23.
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Giant seminoma in an undescended testicle metastasizing to the neck and liver.隐睾内的巨大精原细胞瘤转移至颈部和肝脏。
Mol Clin Oncol. 2016 Jun;4(6):983-985. doi: 10.3892/mco.2016.829. Epub 2016 Mar 22.
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Isolated late metastasis from testicular seminoma presenting as a parotid gland mass: case report and review of the literature.孤立性睾丸精原细胞瘤晚期转移致腮腺肿块:病例报告及文献复习。
Curr Oncol. 2013 Aug;20(4):e354-8. doi: 10.3747/co.20.1489.
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Testicular cancer: seminoma.睾丸癌:精原细胞瘤
BMJ Clin Evid. 2011 Jan 25;2011:1807.
8
Adult extragonadal germ cell tumors.成人性腺外生殖细胞肿瘤。
AJR Am J Roentgenol. 2010 Oct;195(4):W274-80. doi: 10.2214/AJR.09.4103.
9
Cervical lymph node dissection for metastatic testicular cancer.颈淋巴结清扫术治疗转移性睾丸癌。
Ann Surg Oncol. 2010 Jun;17(6):1682-7. doi: 10.1245/s10434-010-1036-x. Epub 2010 Mar 24.
10
Testicular seminoma metastasizing to the parotid gland: report of a case.睾丸精原细胞瘤转移至腮腺:一例报告
Head Neck. 2005 Oct;27(10):923-6. doi: 10.1002/hed.20229.