Gomez-Gallego Carlos, Garcia-Mantrana Izaskun, Salminen Seppo, Collado María Carmen
Functional Foods Forum, Faculty of Medicine, University of Turku, Turku, Finland.
Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Department of Biotechnology, Valencia, Spain.
Semin Fetal Neonatal Med. 2016 Dec;21(6):400-405. doi: 10.1016/j.siny.2016.05.003. Epub 2016 Jun 7.
Beyond its nutritional aspects, human milk contains several bioactive compounds, such as microbes, oligosaccharides, and other substances, which are involved in host-microbe interactions and have a key role in infant health. New techniques have increased our understanding of milk microbiota composition, but few data on the activity of bioactive compounds and their biological role in infants are available. Whereas the human milk microbiome may be influenced by specific factors - including genetics, maternal health and nutrition, mode of delivery, breastfeeding, lactation stage, and geographic location - the impact of these factors on the infant microbiome is not yet known. This article gives an overview of milk microbiota composition and activity, including factors influencing microbial composition and their potential biological relevance on infants' future health.
除了其营养方面，母乳还含有多种生物活性化合物，如微生物、低聚糖和其他物质，它们参与宿主与微生物的相互作用，对婴儿健康起着关键作用。新技术增进了我们对乳汁微生物群组成的了解，但关于生物活性化合物的活性及其在婴儿体内的生物学作用的数据却很少。虽然母乳微生物群可能受到特定因素的影响，包括遗传、母亲健康和营养、分娩方式、母乳喂养、泌乳阶段和地理位置，但这些因素对婴儿微生物群的影响尚不清楚。本文概述了乳汁微生物群的组成和活性，包括影响微生物组成的因素及其对婴儿未来健康的潜在生物学意义。
