Kravtsov E G, Fish N G, Kulinich L I, Alliluev A P, Kotel'nikova O V
Zh Mikrobiol Epidemiol Immunobiol. 1989 Feb(2):29-32.
Samples of Vi-antigen subjected to hydrolysis of different duration have been studied. As revealed in this study, 12-hour hydrolysis causes the depolymerization of the preparation. The fragments thus obtained have been found to possess Vi-specificity. The polymeric form of Vi-antigen contains adhesin differing in specificity from Vi-determinant. This component is absent in the low-molecular fraction of Vi-antigen. Adhesin is the binding element of the molecule of Vi-antigen and ensures its polymeric structure.
对经过不同时长水解的Vi抗原样本进行了研究。本研究表明,12小时的水解会导致制剂解聚。已发现由此获得的片段具有Vi特异性。Vi抗原的聚合形式含有特异性不同于Vi决定簇的粘附素。Vi抗原的低分子部分中不存在该成分。粘附素是Vi抗原分子的结合元件,并确保其聚合结构。