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[Vi抗原制剂的保护特性与其粘附素含量的关系]

[Protective properties of Vi-antigen preparations as dependent on their adhesin content].

作者信息

Alliluev A P, Kotel'nikova O V, Korneeva S A, Fish N G, Kulinich L I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1988 Dec(12):21-6.

PMID:2469269
Abstract

Adhesins contained in the preparation of Vi-antigen have been found to enhance its immunogenic and protective properties. In the preparations of Vi-antigen obtained from Salmonella typhi and Citrobacter freundii the presence of two antigenic determinants has been revealed. One of them is associated with the Vi-receptor and the other determinant, with adhesin. Both determinants take part in the protection of mice from Salmonella infection.

摘要

已发现Vi抗原制剂中所含的黏附素可增强其免疫原性和保护特性。在从伤寒沙门氏菌和弗氏柠檬酸杆菌获得的Vi抗原制剂中,已揭示出两种抗原决定簇的存在。其中一种与Vi受体相关,另一种决定簇与黏附素相关。这两种决定簇均参与保护小鼠免受沙门氏菌感染。

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