Zykin L F, Dunaev G S, Saiamov S R, Sokolov P S
Zh Mikrobiol Epidemiol Immunobiol. 1989 Feb(2):36-40.
Y. pestis L-forms and bacterial forms persist in the body of great gerbils for 40 days. L-forms are poorly phagocytized and can persist in phagocytes for a long time. In guinea pigs immunized with vaccine EV, Y. pestis antigen could be detected till day 160. An unstable L-form was isolated from Ornithodoros mites 3 years after their experimental infection with Y. pestis. Bacterial forms persist in mites for 1-3 years. For 5 years Y. pestis antigen is regularly detected in a high percentage of mites.
鼠疫耶尔森菌L型和细菌型在大沙鼠体内可存活40天。L型菌不易被吞噬,可在吞噬细胞中长期存活。在用EV疫苗免疫的豚鼠中,直到第160天仍可检测到鼠疫耶尔森菌抗原。在用鼠疫耶尔森菌进行实验感染3年后,从钝缘蜱中分离出不稳定的L型菌。细菌型在蜱中可存活1至3年。5年来,在高比例的蜱中可定期检测到鼠疫耶尔森菌抗原。