Núñez-Pereira S, Huhmann N V, Rheinwalt K P, Bullmann V
Spine Surgery Department, St Franziskus Hospital, Köln, Schönsteinstr 63, 50825 Köln, Germany.
Spine Surgery Department, St Franziskus Hospital, Köln, Schönsteinstr 63, 50825 Köln, Germany.
Int J Surg Case Rep. 2016;24:219-22. doi: 10.1016/j.ijscr.2016.04.047. Epub 2016 May 4.
The primary source of spondylodiscitis cannot always be identified. However, not treating the original focus might preclude successful healing due to further spread of the causative microorganisms.
An 80-year-old woman presented with lumbar spondylodiscitis. She received surgical debridement and stabilization with transforaminal lumbar interbody fusion and tailored antibiotic therapy after isolation of Enterococcus spp. Despite appropriate treatment, the patient's condition continued to worsen. An extensive search for the primary infection source finally revealed a rectal fistula caused by a synthetic mesh that had been inserted 7 years before for abdominal sacrocolpopexy. Only after removal of the fistula and protective ileostomy did the patient's condition improved, allowing successful healing of the spondylodiscitis. After a follow-up period of one year no infection relapse was observed.
In cases of spondyodiscitis that are resistant to adequate treatment, a search for infection source must be continued until the focus is found and treated. The presence of uncommon enteric microorganisms causing spondylodiscitis, such as Enterococcus spp., is suggestive of contiguous spread and should therefore be further investigated.
脊椎椎间盘炎的主要感染源并非总能明确。然而,若不治疗原发病灶,致病微生物的进一步扩散可能会妨碍病情的成功治愈。
一名80岁女性因腰椎椎间盘炎就诊。在分离出肠球菌属后,她接受了手术清创,并通过经椎间孔腰椎椎体间融合术进行了固定及针对性抗生素治疗。尽管治疗得当,但患者病情仍持续恶化。对原发感染源进行全面排查后,最终发现是7年前因腹骶阴道固定术植入的合成网片导致了直肠瘘。仅在切除瘘管并进行保护性回肠造口术后,患者病情才有所改善,脊椎椎间盘炎得以成功治愈。随访一年未观察到感染复发。
对于经充分治疗仍有抗药性的脊椎椎间盘炎病例,必须持续寻找感染源,直至找到并治疗病灶。导致脊椎椎间盘炎的罕见肠道微生物(如肠球菌属)的存在提示有邻近扩散,因此应进一步调查。