Franks Peter J, Barker Judith, Collier Mark, Gethin Georgina, Haesler Emily, Jawien Arkadiusz, Laeuchli Severin, Mosti Giovanni, Probst Sebastian, Weller Carolina
Centre for Research & Implementation of Clinical Practice, 128 Hill House, 210 Upper Richmond Road, London SW15 6NP, United Kingdom.
Wounds Australia.
J Wound Care. 2016 Jun;25 Suppl 6:S1-S67. doi: 10.12968/jowc.2016.25.Sup6.S1.
Introduction It is well documented that the prevalence of venous leg ulcers (VLUs) is increasing, coinciding with an ageing population. Accurate global prevalence of VLUs is difficult to estimate due to the range of methodologies used in studies and accuracy of reporting. (1) Venous ulceration is the most common type of leg ulceration and a significant clinical problem, affecting approximately 1% of the population and 3% of people over 80 years of age (2) in westernised countries. Moreover, the global prevalence of VLUs is predicted to escalate dramatically, as people are living longer, often with multiple comorbidities. Recent figures on the prevalence of VLUs are based on a small number of studies, conducted in Western countries, and the evidence is weak. However, it is estimated that 93% of VLUs will heal in 12 months, and 7% remain unhealed after five years. (3) Furthermore, the recurrence rate within 3 months after wound closure is as high as 70%. (4) (-6) Thus, cost-effective adjunct evidence-based treatment strategies and services are needed to help prevent these ulcers, facilitate healing when they occur and prevent recurrence. The impact of a VLU represents social, personal, financial and psychological costs on the individual and further economic drain on the health-care system. This brings the challenge of providing a standardised leg ulcer service which delivers evidence-based treatment for the patient and their ulcer. It is recognised there are variations in practice and barriers preventing the implementation of best practice. There are patients not receiving appropriate and timely treatment in the initial development of VLUs, effective management of their VLU and preventing recurrence once the VLU has healed. Health-care professionals (HCPs) and organisations must have confidence in the development process of clinical practice guidelines and have ownership of these guidelines to ensure those of the highest quality guide their practice. These systematic judgments can assist in policy development, and decision making, improve communication, reduce errors and improve patient outcomes. There is an abundance of studies and guidelines that are available and regularly updated, however, there is still variation in the quality of the services offered to patients with a VLU. There are also variations in the evidence and some recommendations contradict each other, which can cause confusion and be a barrier to implementation. (7) The difference in health-care organisational structures, management support and the responsibility of VLU management can vary in different countries, often causing confusion and a barrier to seeking treatment. These factors further complicate the guideline implementation process, which is generally known to be a challenge with many diseases. (8).
引言 有充分文献记载,随着人口老龄化,下肢静脉溃疡(VLU)的患病率正在上升。由于研究中使用的方法范围和报告的准确性,难以准确估计VLU的全球患病率。(1)静脉溃疡是最常见的腿部溃疡类型,也是一个重大的临床问题,在西方国家影响约1%的人口和80岁以上人群的3%。(2)此外,预计VLU的全球患病率将急剧上升,因为人们的寿命延长,往往伴有多种合并症。关于VLU患病率的最新数据基于在西方国家进行的少数研究,证据薄弱。然而,据估计,93%的VLU将在12个月内愈合,7%在五年后仍未愈合。(3)此外,伤口闭合后3个月内的复发率高达70%。(4)(-6)因此,需要具有成本效益的辅助循证治疗策略和服务,以帮助预防这些溃疡,促进溃疡发生时的愈合并防止复发。VLU的影响对个人而言代表社会、个人、经济和心理成本,对医疗保健系统而言则意味着进一步的经济消耗。这带来了提供标准化腿部溃疡服务的挑战,该服务要为患者及其溃疡提供循证治疗。人们认识到在实践中存在差异以及阻碍最佳实践实施的障碍。在VLU的初始发展阶段,有患者未得到适当和及时的治疗,在VLU愈合后也没有对其进行有效管理和预防复发。医疗保健专业人员(HCP)和组织必须对临床实践指南的制定过程有信心并拥有这些指南,以确保以最高质量的指南指导他们的实践。这些系统的判断有助于政策制定和决策,改善沟通,减少错误并改善患者结局。有大量的研究和指南可供使用且定期更新,然而,为VLU患者提供的服务质量仍然存在差异。证据也存在差异,一些建议相互矛盾,这可能导致困惑并成为实施的障碍。(7)不同国家的医疗保健组织结构、管理支持以及VLU管理的责任可能不同,这常常会造成困惑并成为寻求治疗的障碍。这些因素进一步使指南实施过程复杂化,而这一过程通常被认为是许多疾病面临的挑战。(8)