体外膜肺氧合在成人心肺疾病中的应用。

Extracorporeal membrane oxygenation in cardiopulmonary disease in adults.

机构信息

Division of Pulmonary, Allergy, and Critical Care, Columbia University College of Physicians and Surgeons, New York, New York.

Service de Réanimation Médicale, Groupe Hospitalier Pitié-Salpêtrière, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris-Université Pierre et Marie Curie, Paris, France.

出版信息

J Am Coll Cardiol. 2014 Jul 1;63(25 Pt A):2769-78. doi: 10.1016/j.jacc.2014.03.046. Epub 2014 May 7.

DOI:10.1016/j.jacc.2014.03.046

PMID:24814488

Abstract

The use of extracorporeal membrane oxygenation (ECMO) for both respiratory and cardiac failure in adults is evolving rapidly. Advances in technology and accumulating data are spurring greater interest and explosive growth in ECMO worldwide. Expanding indications and novel strategies are being used. Yet the use of ECMO outpaces the data. The promise of a major paradigm shift for the treatment of respiratory and cardiac failure is tempered by a need for evidence to support many current and potential future uses. The authors review cannulation strategies, indications, and evidence for ECMO in respiratory and cardiac failure in adults as well as potential applications and the impact they may have on current treatment paradigms.

摘要

体外膜肺氧合（ECMO）在成人呼吸和心脏衰竭中的应用正在迅速发展。技术的进步和不断积累的数据正在激发全球对 ECMO 的更大兴趣和爆炸性增长。扩展的适应证和新的策略正在被应用。然而，ECMO 的使用超过了数据。尽管为治疗呼吸和心脏衰竭带来了重大范式转变的希望，但仍需要证据来支持许多当前和潜在的未来用途。作者回顾了成人呼吸和心脏衰竭中 ECMO 的插管策略、适应证和证据，以及潜在的应用及其可能对当前治疗模式产生的影响。