Tracey Marsha L, McHugh Sheena M, Fitzgerald Anthony P, Buckley Claire M, Canavan Ronan J, Kearney Patricia M
Department of Epidemiology and Public Health, University College Cork, Western Road, Western Gateway Building, Cork, Ireland.
Department of Epidemiology and Public Health, University College Cork, Western Road, Western Gateway Building, Cork, Ireland; Department of Statistics, University College Cork, Western Road, Western Gateway Building, Cork, Ireland.
J Diabetes Res. 2016;2016:5975903. doi: 10.1155/2016/5975903. Epub 2016 May 15.
Objective. To explore risk factors for macro- and microvascular complications in a nationally representative sample of adults aged 50 years and over with type 2 diabetes in Ireland. Methods. Data from the first wave of The Irish Longitudinal Study on Ageing (TILDA) (2009-2011) was used in cross-sectional analysis. The presence of doctor diagnosis of diabetes, risk factors, and macro- and microvascular complications were determined by self-report. Gender-specific differences in risk factor prevalence were assessed with the chi-squared test. Binomial regression analysis was conducted to explore independent associations between established risk factors and diabetes-related complications. Results. Among 8175 respondents, 655 were classified as having type 2 diabetes. Older age, being male, a history of smoking, a lower level of physical activity, and a diagnosis of high cholesterol were independent predictors of macrovascular complications. Diabetes diagnosis of 10 or more years, a history of smoking, and a diagnosis of hypertension were associated with an increased risk of microvascular complications. Older age, third-level education, and a high level of physical activity were protective factors (p < 0.05). Conclusions. Early intervention to target modifiable risk factors is urgently needed to reduce diabetes-related morbidity in the older population in Ireland.
目的。在爱尔兰具有全国代表性的50岁及以上2型糖尿病成年人样本中,探究大血管和微血管并发症的危险因素。方法。爱尔兰老龄化纵向研究(TILDA)(2009 - 2011年)第一波的数据用于横断面分析。糖尿病的医生诊断、危险因素以及大血管和微血管并发症通过自我报告确定。危险因素患病率的性别差异采用卡方检验评估。进行二项回归分析以探究既定危险因素与糖尿病相关并发症之间的独立关联。结果。在8175名受访者中,655人被归类为患有2型糖尿病。年龄较大、男性、吸烟史、身体活动水平较低以及高胆固醇诊断是大血管并发症的独立预测因素。糖尿病诊断10年或更长时间、吸烟史以及高血压诊断与微血管并发症风险增加相关。年龄较大、接受高等教育以及身体活动水平较高是保护因素(p < 0.05)。结论。迫切需要针对可改变的危险因素进行早期干预,以降低爱尔兰老年人群中与糖尿病相关的发病率。