Campagna Giuseppe, Zampetti Simona, Gallozzi Alessia, Giansanti Sara, Chiesa Claudio, Pacifico Lucia, Buzzetti Raffaella
Department of Experimental Medicine, Sapienza University, Rome, Italy.
Policlinico Umberto I Hospital, Sapienza University, Rome, Italy.
PLoS One. 2016 Jun 13;11(6):e0156646. doi: 10.1371/journal.pone.0156646. eCollection 2016.
In a previous study, we found that wrist circumference, in particular its bone component, was associated with insulin resistance in a population of overweight/obese children. The aim of the present study was to evaluate the intra- and inter-operator variability in wrist circumference measurement in a population of obese children and adolescents. One hundred and two (54 male and 48 female) obese children and adolescents were consecutively enrolled. In all subjects wrist circumferences were measured by two different operators two times to assess intra- and inter-operator variability. Statistical analysis was performed using SAS v.9.4 and JMP v.12. Measurements of wrist circumference showed excellent inter-operator reliability with Intra class Correlation Coefficients (ICC) of 0.96 and ICC of 0.97 for the first and the second measurement, respectively. The intra-operator reliability was, also, very strong with a Concordance Correlation Coefficient (CCC) of 0.98 for both operators. The high reproducibility demonstrated in our results suggests that wrist circumference measurement, being safe, non-invasive and repeatable can be easily used in out-patient settings to identify youths with increased risk of insulin-resistance. This can avoid testing the entire population of overweight/obese children for insulin resistance parameters.
在之前的一项研究中，我们发现，在超重/肥胖儿童群体中，腕围，尤其是其骨质部分，与胰岛素抵抗相关。本研究的目的是评估肥胖儿童和青少年群体中腕围测量的操作者内和操作者间的变异性。连续纳入了102名（54名男性和48名女性）肥胖儿童和青少年。在所有受试者中，两名不同的操作者对腕围进行了两次测量，以评估操作者内和操作者间的变异性。使用SAS v.9.4和JMP v.12进行统计分析。腕围测量显示出极好的操作者间可靠性，第一次和第二次测量的组内相关系数（ICC）分别为0.96和0.97。操作者内可靠性也非常强，两名操作者的一致性相关系数（CCC）均为0.98。我们的结果中显示的高重复性表明，腕围测量安全、无创且可重复，可轻松用于门诊环境中识别胰岛素抵抗风险增加的青少年。这可以避免对所有超重/肥胖儿童进行胰岛素抵抗参数检测。
