Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran; Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Nutrition. 2017 Nov-Dec;43-44:32-38. doi: 10.1016/j.nut.2017.06.009. Epub 2017 Jul 5.
The predictive potentials of neck and wrist circumferences for cardiometabolic risks in children and adolescents remain to be determined. The aim of this study was to evaluate the association of neck and wrist circumferences with some cardiometabolic risk factors in children and adolescents.
This multicenter study was conducted during the 2014 to 2015 school year with 4200 children and adolescents ages 7 to 18 y. The children were selected by multistage cluster sampling from 30 provinces of Iran. Anthropometric indices (neck, wrist and waist circumference, and body mass index), biochemical and clinical parameters were measured. Metabolic syndrome was defined based on the Adult Treatment Panel III criteria modified for the pediatric age group. High total cholesterol, high low-density lipoprotein cholesterol, and obesity were included as other cardiometabolic risk factors.
The participation rate for blood sampling was 91.5% (n = 3843). The mean (standard deviation) age of participants was 12.3 y (3.2 y). In a multivariate model, neck and wrist circumferences had significant association with elevated blood pressure, low high-density lipoprotein cholesterol, increased body mass index (overweight, excess weight, and generalized obesity), abdominal obesity, and metabolic syndrome. Additionally, obesity had the strongest associations with neck (odds ratio, 1.48; 95% confidence interval, 1.45-1.51) and wrist circumference (odds ratio, 2.25; 95% confidence interval, 2.15-2.36).
Neck and wrist circumferences are associated with some cardiometabolic risk factors. They could be used as alternative clinical tools and easy-to-use indicators of cardiometabolic risk in children and adolescents.
颈围和腕围对儿童和青少年心血管代谢风险的预测潜力仍有待确定。本研究旨在评估颈围和腕围与儿童和青少年某些心血管代谢危险因素的相关性。
这项多中心研究于 2014 年至 2015 学年进行，共有 4200 名 7 至 18 岁的儿童和青少年参加。儿童通过伊朗 30 个省份的多阶段聚类抽样选择。测量了人体测量学指标（颈围、腕围和腰围以及体重指数）、生化和临床参数。代谢综合征根据成人治疗小组 III 标准定义，该标准针对儿科年龄组进行了修改。高总胆固醇、低高密度脂蛋白胆固醇和肥胖被纳入其他心血管代谢危险因素。
血液采样的参与率为 91.5%（n=3843）。参与者的平均（标准差）年龄为 12.3 岁（3.2 岁）。在多变量模型中，颈围和腕围与血压升高、低高密度脂蛋白胆固醇、体重指数增加（超重、超重和全身性肥胖）、腹部肥胖和代谢综合征有显著关联。此外，肥胖与颈围（比值比，1.48；95%置信区间，1.45-1.51）和腕围（比值比，2.25；95%置信区间，2.15-2.36）的关联最强。
颈围和腕围与某些心血管代谢危险因素相关。它们可以作为替代的临床工具，并且是儿童和青少年心血管代谢风险的简便易用指标。
