单核细胞/高密度脂蛋白胆固醇比值可预测 ST 段抬高型心肌梗死患者住院期间及五年内的死亡率。
Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction.
机构信息
Department of Cardiology, Turkiye Yuksek Ihtisas Education and R esearch Hospital, Ankara, Turkey.
出版信息
Cardiol J. 2016;23(5):505-512. doi: 10.5603/CJ.a2016.0026. Epub 2016 Jun 14.
BACKGROUND
We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.
METHODS
A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.
RESULTS
MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308-5.950), in-hospital MACE (HR 1.501, 95% CI 1.015-1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225-4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064-1.552, p = 0.009).
CONCLUSIONS
MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.
背景
我们评估单核细胞与高密度脂蛋白胆固醇比值（MHR）在预测 ST 段抬高型心肌梗死（STEMI）患者住院期间和 5 年死亡率及主要不良心血管事件（MACE）中的价值。
方法
共纳入 1598 例患者，根据 MHR 值分为三分位组。采用 Cox 回归分析评估不同变量对临床结局的影响。
结果
MHR 是住院期间死亡率（HR=3.745，95%CI 1.308-5.950）、住院期间 MACE（HR=1.501，95%CI 1.015-1.993，p=0.022）、5 年死亡率（HR=2.048，95%CI 1.225-4.091，p=0.014）和 5 年 MACE（HR=1.285，95%CI 1.064-1.552，p=0.009）的独立预测因素。
结论
MHR 是 STEMI 患者住院期间及长期死亡率和 MACE 的独立预测因素。
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