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活性成分在多糖-蛋白质复合凝聚体中的包封。

Encapsulation of active ingredients in polysaccharide-protein complex coacervates.

机构信息

Department of Science and Humanities, National Institute of Technology Nagaland, Chumukedima-797103, India.

Department of Chemical Sciences, Tezpur University, Napaam 784028, India.

出版信息

Adv Colloid Interface Sci. 2017 Jan;239:136-145. doi: 10.1016/j.cis.2016.05.009. Epub 2016 Jun 2.

Abstract

Polysaccharide-protein complex coacervates are amongst the leading pair of biopolymer systems that has been used over the past decades for encapsulation of numerous active ingredients. Complex coacervation of polysaccharides and proteins has received increasing research interest for the practical application in encapsulation industry since the pioneering work of complex coacervation by Bungenburg de Jong and co-workers on the system of gelatin-acacia, a protein-polysaccharide system. Because of the versatility and numerous potential applications of these systems essentially in the fields of food, pharmaceutical, cosmetics and agriculture, there has been intense interest in recent years for both fundamental and applied studies. Precisely, the designing of the micronscale and nanoscale capsules for encapsulation and control over their properties for practical applications garners renewed interest. This review discusses on the overview of polysaccharide-protein complex coacervates and their use for the encapsulation of diverse active ingredients, designing and controlling of the capsules for delivery systems and developments in the area.

摘要

多糖-蛋白质复合凝聚物是过去几十年中用于封装多种活性成分的主要生物聚合物体系之一。多糖和蛋白质的复合凝聚物因其在封装工业中的实际应用而受到越来越多的研究关注,这要归功于 Bungenburg de Jong 及其同事在明胶-阿拉伯胶体系上的开创性工作,该体系是一种蛋白质-多糖体系。由于这些体系在食品、制药、化妆品和农业等领域具有多功能性和众多潜在应用,近年来人们对基础研究和应用研究都产生了浓厚的兴趣。具体来说,对于微米级和纳米级胶囊的封装设计及其对实际应用的性能控制引起了新的关注。本文综述了多糖-蛋白质复合凝聚物及其在封装多种活性成分中的应用,讨论了胶囊的设计和控制用于输送系统以及该领域的发展。

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