Xu Guangzhong, Wang Zheng, Yu Chengyuan, Amin Buhe, Du Dexiao, Li Tianxiong, Chen Guanyang, Wang Liang, Li Zhehong, Chen Weijian, Tian Chenxu, Wuyun Qiqige, Sang Qing, Shang Mingyue, Lian Dongbo, Zhang Nengwei
Surgery Centre of Diabetes Mellitus, Capital Medical University Affiliated Beijing Shijitan Hospital, Beijing, People's Republic of China.
Surgery Centre of Diabetes Mellitus, Peking University Ninth School of Clinical Medicine, Beijing, People's Republic of China.
Diabetes Metab Syndr Obes. 2023 Apr 12;16:1029-1042. doi: 10.2147/DMSO.S389346. eCollection 2023.
Many studies have reported that bariatric surgery may reduce postoperative cardiovascular risk in patient with obesity, but few have addressed this risk in the Chinese population.
To assess the impact of bariatric surgery on cardiovascular disease (CVD) risk in the Chinese population using the World Health Organization (WHO) risk model, the Global risk model, and the Framingham Risk Score.
We retrospectively analyzed data collected on patient with obesity who underwent bariatric surgery at our institution between March 2009 and January 2021. Their demographic characteristics, anthropometric variables, and glucolipid metabolic parameters were assessed preoperatively and at their 1-year postoperative follow-up. Subgroup analysis compared body mass index (BMI) < 35 kg/m and BMI ≥ 35 kg/m, as well as gender. We used the 3 models to calculate their CVD risk.
We evaluated 61 patients, of whom 26 (42.62%) had undergone sleeve gastrectomy (SG) surgery and 35 (57.38%) Roux-en-Y gastric bypass (RYGB) surgery. Of the patients with BMI ≥ 35 kg/m, 66.67% underwent SG, while 72.97% with BMI < 35 kg/m underwent RYGB. HDL levels were significantly higher at 12 months postoperatively relative to baseline. When the models were applied to calculate CVD risk in Chinese patients with obesity, the 1-year CVD risk after surgery were reduced lot compared with the preoperative period.
Patient with obesity had significantly lower CVD risks after bariatric surgery. This study also demonstrates that the models are reliable clinical tools for assessing the impact of bariatric surgery on CVD risk in the Chinese population.
许多研究报告称，减肥手术可能会降低肥胖患者术后的心血管疾病风险，但针对中国人群这一风险的研究较少。
使用世界卫生组织（WHO）风险模型、全球风险模型和弗雷明汉风险评分，评估减肥手术对中国人群心血管疾病（CVD）风险的影响。
我们回顾性分析了2009年3月至2021年1月期间在我院接受减肥手术的肥胖患者的数据。在术前和术后1年随访时评估他们的人口统计学特征、人体测量变量和糖脂代谢参数。亚组分析比较了体重指数（BMI）<35kg/m²和BMI≥35kg/m²的患者，以及不同性别患者。我们使用这三种模型计算他们的心血管疾病风险。
我们评估了61例患者，其中26例（42.62%）接受了袖状胃切除术（SG），35例（57.38%）接受了Roux-en-Y胃旁路术（RYGB）。BMI≥35kg/m²的患者中，66.67%接受了SG，而BMI<35kg/m²的患者中，72.97%接受了RYGB。术后12个月时高密度脂蛋白水平相对于基线显著升高。当应用这些模型计算中国肥胖患者的心血管疾病风险时，术后1年的心血管疾病风险与术前相比大幅降低。
肥胖患者在接受减肥手术后心血管疾病风险显著降低。本研究还表明，这些模型是评估减肥手术对中国人群心血管疾病风险影响的可靠临床工具。
