Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Stockholm, Sweden; email:
Annu Rev Cell Dev Biol. 2016 Oct 6;32:127-141. doi: 10.1146/annurev-cellbio-111315-124953. Epub 2016 Jun 1.
The brain constantly changes to store memories and adapt to new conditions. One type of plasticity that has gained increasing interest during the last years is the generation of new cells. The generation of both new neurons and glial cells contributes to neural plasticity and to some neural repair. There are substantial differences between mammalian species with regard to the extent of and mechanisms behind cell exchange in neural plasticity. Both neurogenesis and gliogenesis have several specific features in humans, which may contribute to the unique plasticity of the human brain.
大脑不断变化以存储记忆并适应新的条件。近年来,一种越来越受到关注的可塑性是产生新的细胞。新神经元和神经胶质细胞的产生都有助于神经可塑性和一些神经修复。在哺乳动物物种之间,细胞交换的程度和机制存在很大差异,这与神经可塑性有关。神经发生和神经胶质发生在人类中具有几个特定的特征,这可能有助于人类大脑的独特可塑性。