尿液中滥用药物检测的六种方法评估。

An evaluation of six methods for the detection of drugs of abuse in urine.

作者信息

Simpson D, Jarvie D R, Heyworth R

机构信息

University Department of Clinical Chemistry, Royal Infirmary, Edinburgh, UK.

出版信息

Ann Clin Biochem. 1989 Mar;26 ( Pt 2):172-81. doi: 10.1177/000456328902600215.

DOI:10.1177/000456328902600215

PMID:2729861

Abstract

The detection of drugs of abuse in urine by four commercial immunoassay systems (TDx, BCL and PFI-20 opiates, and PFI-20 morphine) and one commercial TLC system (Toxi-Lab) was investigated and results compared with those obtained by a dual-column capillary GC system. The TDx system was the most reliable method for preliminary screening of urines for opiates; all the commercial immunoassay systems gave some results which were at variance with those of the GC. The GC method proved to be more reliable than the commercial TLC system in discriminating between the different opiates and is recommended for identification of drugs of abuse in urine specimens in which positive results have been obtained with preliminary screening procedures.

摘要

研究了四种商用免疫分析系统（TDx、BCL和PFI - 20阿片类药物检测系统以及PFI - 20吗啡检测系统）和一种商用薄层色谱系统（Toxi - Lab）对尿液中滥用药物的检测情况，并将结果与通过双柱毛细管气相色谱系统获得的结果进行了比较。TDx系统是对尿液进行阿片类药物初步筛查最可靠的方法；所有商用免疫分析系统给出的一些结果与气相色谱法的结果存在差异。在区分不同阿片类药物方面，气相色谱法被证明比商用薄层色谱系统更可靠，因此推荐用于对初步筛查程序呈阳性的尿液标本中的滥用药物进行鉴定。