Digre K B, Durcan F J, Branch D W, Jacobson D M, Varner M W, Baringer J R
Department of Neurology, University of Utah Medical Center, Salt Lake City 84132.
Ann Neurol. 1989 Mar;25(3):228-32. doi: 10.1002/ana.410250304.
In more than 50% of amaurosis fugax patients under 45 years of age no cause for the episodes of visual loss is identifiable. We have encountered 6 young adults (4 women and 2 men) with episodes of amaurosis fugax associated with elevated levels of antiphospholipid antibodies. Splinter hemorrhages of the nail beds were present in most patients. Treatment with antiplatelet medications and anticoagulants appeared to reduce the frequency of episodes and might prevent central retinal artery occlusions or stroke.
在45岁以下的一过性黑矇患者中,超过50%的患者无法确定视力丧失发作的原因。我们遇到过6例年轻成人(4名女性和2名男性),其一过性黑矇发作与抗磷脂抗体水平升高有关。大多数患者存在甲床裂片样出血。使用抗血小板药物和抗凝剂治疗似乎可降低发作频率,并可能预防视网膜中央动脉阻塞或中风。